NIDA-41020

NIDA-41020 Structure
NIDA-41020 structure
Common Name NIDA-41020
CAS Number 502486-89-7 Molecular Weight 459.36800
Density N/A Boiling Point N/A
Molecular Formula C23H24Cl2N4O2 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS06
GHS06
Signal Word Danger

Keynote review: Medicinal chemistry strategies to CB1 cannabinoid receptor antagonists

Drug Discov. Today 10 , 693-702, (2005)

The proven clinical efficacy of the CB1 cannabinoid receptor antagonist rimonabant in obesity and its further therapeutic potential has given a tremendous impetus to the discovery of novel CB1 antagonists.

Synthesis, structure-activity relationship, and evaluation of SR141716 analogues: development of central cannabinoid receptor ligands with lower lipophilicity.

J. Med. Chem. 46 , 642-645, (2003)

Exploration of the central CB1 cannabinoid receptors using positron emission tomography (PET) will allow for an understanding of the pharmacological and physiological role played by these receptors in the CNS. Current tracers are highly lipophilic compounds t...