2-Amino-4-methylpentanoic acid

2-Amino-4-methylpentanoic acid Structure
2-Amino-4-methylpentanoic acid structure
Common Name 2-Amino-4-methylpentanoic acid
CAS Number 328-39-2 Molecular Weight 131.173
Density 1.0±0.1 g/cm3 Boiling Point 225.8±23.0 °C at 760 mmHg
Molecular Formula C6H13NO2 Melting Point 293-296ºC
MSDS Chinese USA Flash Point 90.3±22.6 °C

Activation of Tomato Bushy Stunt Virus RNA-Dependent RNA Polymerase by Cellular Heat Shock Protein 70 Is Enhanced by Phospholipids In Vitro.

J. Virol. 89(10) , 5714-23, (2015)

Similar to other positive-strand RNA viruses, tombusviruses are replicated by the membrane-bound viral replicase complex (VRC). The VRC consists of the p92 virus-coded RNA-dependent RNA polymerase (RdRp), the viral p33 RNA chaperone, and several co-opted host...

Comparison of Mannose, Ethylene Glycol, and Methoxy-Terminated Diluents on Specificity and Selectivity of Electrochemical Peptide-Based Sensors.

Anal. Chem. 87 , 6966-73, (2015)

We report the synthesis and application of three new antifouling diluents for the fabrication of an E-PB HIV sensor. Among the three thiolated antifouling diluents used in this study, the methoxy-terminated diluent (C6-MEG) is the most effective in alleviatin...

Improved characterization of EV preparations based on protein to lipid ratio and lipid properties.

PLoS ONE 10(3) , e0121184, (2015)

In recent years the study of extracellular vesicles has gathered much scientific and clinical interest. As the field is expanding, it is becoming clear that better methods for characterization and quantification of extracellular vesicles as well as better sta...

Glucocorticoids retard skeletal muscle development and myoblast protein synthesis through a mechanistic target of rapamycin (mTOR)-signaling pathway in broilers (Gallus gallus domesticus).

Stress 18 , 686-98, (2015)

Glucocorticoids exert a well-known catabolic protein action on skeletal muscle. The mechanistic target of rapamycin (mTOR) signaling pathway acts as a central regulator of protein metabolism. Whether glucocorticoids regulate protein synthesis through the mTOR...

The effects of resistance exercise training on macro- and micro-circulatory responses to feeding and skeletal muscle protein anabolism in older men.

J. Physiol. 593 , 2721-34, (2015)

Increases in limb blood flow in response to nutrition are reduced in older age. Muscle microvascular blood flow (MBF) in response to nutrition is also reduced with advancing age and this may contribute to age-related 'anabolic resistance'. Resistance exercise...

The Analysis of Pendolino (peo) Mutants Reveals Differences in the Fusigenic Potential among Drosophila Telomeres.

PLoS Genet. 11 , e1005260, (2015)

Drosophila telomeres are sequence-independent structures that are maintained by transposition to chromosome ends of three specialized retroelements (HeT-A, TART and TAHRE; collectively designated as HTT) rather than telomerase activity. Fly telomeres are prot...

Anthocyanins and antioxidant capacities of six Chilean berries by HPLC-HR-ESI-ToF-MS.

Food Chem. 176 , 106-14, (2015)

The HPLC profiles of six fruits endemic of the VIII region of Chile were investigated using high resolution mass analysis (HR-ToF-ESI-MS). The anthocyanin fingerprints generated for the fruits were compared and the antioxidant capacities measured by the scave...

Comparative proteomic analyses reveal that Gnt2-mediated N-glycosylation affects cell wall glycans and protein content in Fusarium oxysporum.

J. Proteomics 128 , 189-202, (2015)

Protein N-glycosylation is a ubiquitous post-translational modification that contributes to appropriate protein folding, stability, functionality and localization. N-glycosylation has been identified as an important process for morphogenesis and virulence in ...

General unknown screening for pesticides in whole blood and Korean gastric contents by liquid chromatography-tandem mass spectrometry.

Arch. Pharm. Res. 37(10) , 1317-24, (2014)

A method of simultaneously screening 215 types of pesticides has been established by liquid chromatography with tandem mass spectrometry, quadrupole/time of flight mass spectrometry and triple quadrupole mass spectrometry. Samples of blood and gastric content...

Liquid-liquid extraction and liquid chromatography-mass spectrometry detection of curcuminoids from bacterial culture medium.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 988 , 116-20, (2015)

Liquid chromatography-mass spectrometry (LC-MS) has been used to detect polyphenolic curcuminoids found in turmeric but studies of metabolism by bacterial and mammalian cells in vitro are compromised by poor recovery from the culture medium. We report a liqui...