![]() Tetracycline hydrochloride structure
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Common Name | Tetracycline hydrochloride | ||
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CAS Number | 64-75-5 | Molecular Weight | 480.896 | |
Density | N/A | Boiling Point | 799.4ºC at 760 mmHg | |
Molecular Formula | C22H25ClN2O8 | Melting Point | 220-223 °C(lit.) | |
MSDS | Chinese USA | Flash Point | 437.3ºC | |
Symbol |
![]() GHS07 |
Signal Word | Warning |
Selective growth-inhibitory effect of 8-hydroxyquinoline towards Clostridium difficile and Bifidobacterium longum subsp. longum in co-culture analysed by flow cytometry.
J. Med. Microbiol. 63(Pt 12) , 1663-9, (2014) The major risk factor for Clostridium difficile infection (CDI) is the use of antibiotics owing to the disruption of the equilibrium of the host gut microbiota. To preserve the beneficial resident probiotic bacteria during infection treatment, the use of mole... |
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Pre-microRNA binding aminoglycosides and antitumor drugs as inhibitors of Dicer catalyzed microRNA processing.
Bioorg. Med. Chem. Lett. 22 , 1709-11, (2012) Over-expressions of miRNAs are being increasingly linked with many diseases including different types of cancer. In this study, the role of some known small molecular therapeutics has been investigated for their ability to bind with the pre-miRNA target (hsa-... |
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Development of a Method for the Analysis of Multiclass Antibiotic Residues in Milk Using QuEChERS and Liquid Chromatography-Tandem Mass Spectrometry.
Foodborne Pathog. Dis. 12 , 693-703, (2015) A precise and simplified method of sample preparation for the simultaneous quantification of the antibiotics β-lactam, macrolide, tetracycline, sulfonamide, and quinolone in bovine milk was developed. The central composite design of response surface methodolo... |
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Removal of tetracycline from aqueous solution by a Fe3O4 incorporated PAN electrospun nanofiber mat.
J. Environ. Sci. (China) 28 , 29-36, (2015) Pollution of antibiotics, a type of emerging contaminant, has become an issue of concern, due to their overuse in human and veterinary application, persistence in environment and great potential risk to human and animal health even at trace level. In this wor... |
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Antagonistic control of a dual-input mammalian gene switch by food additives.
Nucleic Acids Res. 42(14) , e116, (2014) Synthetic biology has significantly advanced the design of mammalian trigger-inducible transgene-control devices that are able to programme complex cellular behaviour. Fruit-based benzoate derivatives licensed as food additives, such as flavours (e.g. vanilla... |
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Origins of Yersinia pestis sensitivity to the arylomycin antibiotics and the inhibition of type I signal peptidase.
Antimicrob. Agents Chemother. 59 , 3887-98, (2015) Yersinia pestis is the etiologic agent of the plague. Reports of Y. pestis strains that are resistant to each of the currently approved first-line and prophylactic treatments point to the urgent need to develop novel antibiotics with activity against the path... |
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Antibiotic exposure in a low-income country: screening urine samples for presence of antibiotics and antibiotic resistance in coagulase negative staphylococcal contaminants.
PLoS ONE 9(12) , e113055, (2014) Development of antimicrobial resistance has been assigned to excess and misuse of antimicrobial agents. Staphylococci are part of the normal flora but are also potential pathogens that have become essentially resistant to many known antibiotics. Resistances i... |
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Enhanced osteointegration on tantalum-implanted polyetheretherketone surface with bone-like elastic modulus.
Biomaterials 51 , 173-83, (2015) Polyetheretherketone (PEEK) possesses a similar elastic modulus as bones but yet suffers from bio-inertness and poor osteogenesis. In this work, tantalum ions are implanted energetically into PEEK by plasma immersion ion implantation (PIII) to form Ta2O5 nano... |
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A novel mouse model identifies cooperating mutations and therapeutic targets critical for chronic myeloid leukemia progression.
J. Exp. Med. 212 , 1551-69, (2015) The introduction of highly selective ABL-tyrosine kinase inhibitors (TKIs) has revolutionized therapy for chronic myeloid leukemia (CML). However, TKIs are only efficacious in the chronic phase of the disease and effective therapies for TKI-refractory CML, or... |
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The application of laser microdissection in molecular detection and identification of aspergillus fumigatus from murine model of acute invasive pulmonary aspergillosis.
Mycopathologia 178(1-2) , 53-61, (2014) Invasive aspergillosis (IA) is a major concern in patients with severe immune deficiency. As antifungal susceptibility varies in different fungal pathogens, accurate and timely identification of species is becoming imperative for guidance of therapy and reduc... |