Tetracaine
Tetracaine structure
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Common Name | Tetracaine | ||
|---|---|---|---|---|
| CAS Number | 94-24-6 | Molecular Weight | 264.363 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 389.4±27.0 °C at 760 mmHg | |
| Molecular Formula | C15H24N2O2 | Melting Point | 43 °C | |
| MSDS | Chinese USA | Flash Point | 189.3±23.7 °C | |
| Symbol |
GHS06, GHS08 |
Signal Word | Danger | |
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Effect of melatonin and analogues on corneal wound healing: involvement of Mt2 melatonin receptor.
Curr. Eye Res. 40(1) , 56-65, (2014) We have investigated the effect of melatonin and its analogues on rabbit corneal epithelial wound healing.New Zealand rabbits were anaesthetised and wounds were made by placing Whatman paper discs soaked in n-heptanol on the cornea. Melatonin and analogues (a... |
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Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Chem. Res. Toxicol. 23 , 171-83, (2010) Drug-induced liver injury is one of the main causes of drug attrition. The ability to predict the liver effects of drug candidates from their chemical structures is critical to help guide experimental drug discovery projects toward safer medicines. In this st... |
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Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
J. Med. Chem. 48 , 3269-79, (2005) Growing interest in the use of both the logarithm of the partition coefficient of the neutral species in the alkane/water system (log P(N)(alk)) and the difference between log P(N)(oct) (the logarithm of the partition coefficient of the neutral species in the... |
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Cucurbit(6)uril immobilized on silica: a novel high-performance liquid chromatographic stationary phase.
J. Sep. Sci. 38(7) , 1082-9, (2015) In the present study, one of the new generation of host molecules, cucurbit(6)uril (CB(6)), was immobilized onto silica (CB(6)/SiO2 ) by a sol-gel approach. CB(6)/SiO2 was characterized by NMR spectroscopy, Fourier transform infrared spectroscopy, thermogravi... |
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Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
J. Med. Chem. 51 , 6740-51, (2008) The work provides a new model for the prediction of the MAO-A and -B inhibitor activity by the use of combined complex networks and QSAR methodologies. On the basis of the obtained model, we prepared and assayed 33 coumarin derivatives, and the theoretical pr... |
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Calcium regulation in aortic smooth muscle cells during the initial phase of tunicamycin-induced endo/sarcoplasmic reticulum stress.
Eur. J. Pharmacol. 735 , 86-96, (2014) Endo/sarcoplasmic reticulum stress and the unfolded protein response have been implicated as underlying mechanisms of cell death in many pathological conditions. We have confirmed that long-term exposure to 10µM tunicamycin induced the endo/sarcoplasmic retic... |
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Eliminating antibiotic prophylaxis for intravitreal injections: a consecutive series of 18,839 injections by a single surgeon.
Retina (Philadelphia, Pa.) 35(4) , 783-8, (2015) By optimizing the protocol for intravitreal injections, the risk of endophthalmitis can be minimized. This study assesses the incidence of endophthalmitis and other complications after a consecutive series of intravitreal injections where all antibiotics were... |
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Investigation on performance of zirconia and magnesia-zirconia stationary phases in hydrophilic interaction chromatography.
Talanta 129 , 438-47, (2014) In the current study, zirconia (ZrO2) and its composite, magnesia-zirconia (MgO-ZrO2), were prepared as the hydrophilic interaction chromatographic (HILIC) stationary phases (SPs). Different experimental variables including water content, pH and buffer concen... |
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The levels of Brachyspira hyodysenteriae binding to porcine colonic mucins differ between individuals, and binding is increased to mucins from infected pigs with de novo MUC5AC synthesis.
Infect. Immun. 83(4) , 1610-9, (2015) Brachyspira hyodysenteriae colonizes the pig colon, resulting in mucohemorrhagic diarrhea and growth retardation. Fecal mucus is a characteristic feature of swine dysentery; therefore, we investigated how the mucin environment changes in the colon during infe... |
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QSAR-based solubility model for drug-like compounds.
Bioorg. Med. Chem. 18 , 7078-84, (2010) Solubility plays a very important role in the selection of compounds for drug screening. In this context, a QSAR model was developed for predicting water solubility of drug-like compounds. First, a set of relevant parameters for establishing a drug-like chemi... |