Nitrazepam

Nitrazepam Structure
Nitrazepam structure
Common Name Nitrazepam
CAS Number 146-22-5 Molecular Weight 281.26600
Density 1.4 g/cm3 Boiling Point 497ºC at 760 mmHg
Molecular Formula C15H11N3O3 Melting Point 226-229ºC
MSDS Chinese USA Flash Point 254.4ºC
Symbol GHS07
GHS07
Signal Word Warning

Sedative-hypnotics are widely abused by drivers apprehended for driving under the influence of drugs.

Ther. Drug Monit. 37 , 339-46, (2015)

Sedative-hypnotics are commonly encountered in drivers apprehended for driving under the influence of drugs (DUID). Previous research has mainly concentrated on the residual effects of the drugs.In this study, the extent of sleep medication use and abuse amon...

Determination of low levels of benzodiazepines and their metabolites in urine by hollow-fiber liquid-phase microextraction (LPME) and gas chromatography-mass spectrometry (GC-MS).

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 975 , 24-33, (2014)

In this study, it is shown a method for the determination of benzodiazepines and their main metabolites in urine samples by hollow-fiber liquid-phase microextraction (LPME) in the three-phase mode. Initially, the hydrolysis step was performed using 100 μL of ...

Cleaning up blood samples using a modified "QuEChERS" procedure for the determination of drugs of abuse and benzodiazepines by UPLC-MSMS(☆).

Forensic Sci. Int. 243 , 99-106, (2014)

The "QuEChERS" (quick, easy, cheap, effective, rugged, and safe) dispersive SPE (dSPE) method is an emerging sample preparation technique that is becoming increasingly popular in the area of multi-residue pesticide analysis in food and agricultural products. ...

Simple and sensitive screening and quantitative determination of 88 psychoactive drugs and their metabolites in blood through LC–MS/MS: Application on postmortem samples

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 970 , 1-7, (2014)

• The introduction has been modified. • More references have been added to the text. • Limitations of the method have been discussed more in detail.

Urine Mescaline Screening With a Biochip Array Immunoassay and Quantification by Gas Chromatography-Mass Spectrometry.

Ther. Drug Monit. 37 , 805-11, (2015)

Mescaline, the primary psychoactive chemical in peyote cactus, has been consumed for thousands of years in ancient religious ceremonies. The US military wanted to determine if mescaline intake was a problem for personnel readiness. Twenty thousand seventeen u...

[The withdrawal syndrome in benzodiazepine dependence and its management].

Rev. Med. Chir. Soc. Med. Nat. Iasi. 113(3) , 879-84, (2009)

The authors present the result of an observational study about the withdrawal syndrome in benzodiazepine dependence, and the aspect of identifying withdrawal symptoms, effective communication with the patient and the structure of withdrawal programmes.The stu...

[Simultaneous determination of 5 sedative hypnotics in human plasma by reversed phase high-performance liquid chromatography].

Zhong Nan Da Xue Xue Bao. Yi Xue Ban 34(7) , 689-92, (2009)

To determine diazepam, nitrazepam, oxazepam, estazolam, and alprazolam simultaneously in human plasma by reversed phase high-performance liquid chromatography (RP-HPLC).Ten microliter carbamazepine (50 mg/L)as the internal standard was added into 1 mL sample,...

[Renal effect of treatment for heart failure].

Ugeskr. Laeg. 171(9) , 718, (2009)

The case of a 66-year-old male with heart failure and cardiorenal syndrome is presented. The patient had normal renal function before intensive treatment with diuretics and ACE inhibitor. Shortly after the ACE inhibitor was stopped and diuretics were either s...

Treatment of infantile spasms with sodium valproate followed by benzodiazepines.

J. Med. Assoc. Thai. 90(10) , 2244, (2007)

Treatment of infantile spasms with sodium valproate followed by benzodiazepines.

J. Med. Assoc. Thai. 90(9) , 1809-14, (2007)

To review the result of the infantile spasms' treatment with sodium valproate followed by nitrazepam or clonazepam.Descriptive retrospective study.Srinagarind Hospital, Department of Pediatrics, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.T...