Phenylglyoxylic acid

Phenylglyoxylic acid Structure
Phenylglyoxylic acid structure
Common Name Phenylglyoxylic acid
CAS Number 611-73-4 Molecular Weight 150.131
Density 1.3±0.1 g/cm3 Boiling Point 258.6±13.0 °C at 760 mmHg
Molecular Formula C8H6O3 Melting Point 62-65 °C(lit.)
MSDS Chinese USA Flash Point 124.4±16.3 °C
Symbol GHS07
GHS07
Signal Word Warning

Development of a multi-residue method in a fetal matrix: analysis of meconium.

Anal. Bioanal. Chem 406(30) , 7785-97, (2014)

Meconium is the earliest stool of newborns. It is a complex matrix that reflects the degree of fetal exposure to environmental pollutants. To investigate exposure to xenobiotics, an analytical method was developed to identify and quantify some pesticides and ...

Development of liquid chromatography methods coupled to mass spectrometry for the analysis of substances with a wide variety of polarity in meconium.

Talanta 138 , 231-9, (2015)

Meconium is the first fecal excretion of newborns. This complex accumulative matrix allows assessing the exposure of the fetus to xenobiotics during the last 6 months of pregnancy. To determine the eventual effect of fetal exposure to micropollutants in this ...

Copper/alpha-ketocarboxylate chemistry with supporting peralkylated diamines: reactivity of copper(I) complexes and dicopper-oxygen intermediates.

Inorg. Chem. 49(7) , 3531-9, (2010)

To further understand copper-promoted oxidation reactions, the Cu(I) complexes LCuX (L = N,N'-di-tert-butyl-N,N'-dimethylethylenediamine; X = benzoylformate (BF) or p-nitro-benzoylformate) were synthesized, fully characterized by X-ray crystallography and spe...

Simultaneous determination of aromatic acid metabolites of styrene and styrene-oxide in rat urine by gas chromatography-flame ionization detection.

J. Anal. Toxicol. 36(5) , 312-8, (2012)

A convenient and reliable gas chromatographic method was developed for the simultaneous determination of six aromatic acid metabolites of styrene and styrene-oxide in rat urine; i.e., benzoic (BA), phenylacetic (PAA), mandelic (MA), phenylglyoxylic (PGA), hip...

DNA damage and susceptibility assessment in industrial workers exposed to styrene.

J. Toxicol. Environ. Health A 75(13-15) , 735-46, (2012)

Styrene is a widely used chemical in the manufacture of synthetic rubber, resins, polyesters, and plastics. The highest levels of human exposure to styrene occur during the production of reinforced plastic products. The objective of this study was to examine ...

Occupational exposure to styrene in the fibreglass reinforced plastic industry: comparison between two different manufacturing processes.

Med. Lav. 103(5) , 402-12, (2012)

Styrene is used in manufacturing fiberglass reinforced plastics: and occupational exposure was related to neurotoxicology and genotoxicity. The sum of the metabolites mandelic and phenylglyoxylic acids is the ACGIH biomarker for occupational exposure with a B...

Rationally re-designed mutation of NAD-independent L-lactate dehydrogenase: high optical resolution of racemic mandelic acid by the engineered Escherichia coli.

Microb. Cell Fact. 11 , 151, (2012)

NAD-independent L-lactate dehydrogenase (L-iLDH) from Pseudomonas stutzeri SDM can potentially be used for the kinetic resolution of small aliphatic 2-hydroxycarboxylic acids. However, this enzyme showed rather low activity towards aromatic 2-hydroxycarboxyli...

Immobilization of membrane-bounded (S)-mandelate dehydrogenase in sol-gel matrix for electroenzymatic synthesis.

Bioelectrochemistry 104 , 65-70, (2015)

Membrane-bounded (S)-mandelate dehydrogenase has been immobilized on the surface of glassy carbon and carbon felt electrodes by encapsulation in a silica film obtained by sol-gel chemistry. Such bioelectrochemical system has been used for the first time for e...

Substrate specificity in thiamin diphosphate-dependent decarboxylases.

Bioorg. Chem. 43 , 26-36, (2012)

Thiamin diphosphate (ThDP) is the biologically active form of vitamin B(1), and ThDP-dependent enzymes are found in all forms of life. The catalytic mechanism of this family requires the formation of a common intermediate, the 2α-carbanion-enamine, regardless...

Occupational styrene exposure and hearing loss: a cohort study with repeated measurements.

Int. Arch. Occup. Environ. Health 82(4) , 463-80, (2009)

Associations between occupational styrene exposure and impairment of hearing function were investigated, guided by three questions: are there hearing losses concerning high frequency and standard audiometric test? Are there dose-response relationships and mea...