Avermectin

Avermectin Structure
Avermectin structure
Common Name Avermectin
CAS Number 71751-41-2 Molecular Weight 1732.13
Density 1.2±0.1 g/cm3 Boiling Point 940.9±65.0 °C at 760 mmHg
Molecular Formula C95H142O28 Melting Point 150-155°C
MSDS Chinese USA Flash Point 268.1±27.8 °C
Symbol GHS06 GHS08 GHS09
GHS06, GHS08, GHS09
Signal Word Danger

Toxicity of three insecticides to Lysiphlebus fabarum, a parasitoid of the black bean aphid, Aphis fabae.

J. Insect Sci. 11 , 104, (2011)

The toxicity of three insecticides to Lysiphlebus fabarum (Marshall) (Hymenoptera: Braconidae: Aphidiinae), a parasitoid of Aphis fabae Scopoli (Hemiptera: Aphididae), was investigated using IOBC/wprs protocols. Abamectin 1.8 EC, imidacloprid 350 SC, and pyme...

[Toxicity and bioactivity of several alternative nematocides against Ditylenchus destructor].

Ying Yong Sheng Tai Xue Bao 22(11) , 3026-32, (2011)

By the methods of fumigation and contact assay, this paper determined the toxicity of four kinds of soil fumigants and six kinds of non-fumigants against Ditylenchus destructor. In the meantime, the bioactivity of the agents was evaluated by the corrected mor...

Determination of active substances in binary mixture antiparasitic veterinary formulations by HPLC.

Acta Pol. Pharm. 68(4) , 467-72, (2011)

The purpose of the study was to develop a simple, versatile HPLC method for the identification and quantification of praziquantel and ivermectin (in Equimax) or praziquantel and abamectin (in Abamitel Plus). A satisfactory separation was obtained using the Su...

The river blindness drug Ivermectin and related macrocyclic lactones inhibit WNT-TCF pathway responses in human cancer.

EMBO Mol. Med. 6(10) , 1263-78, (2014)

Constitutive activation of canonical WNT-TCF signaling is implicated in multiple diseases, including intestine and lung cancers, but there are no WNT-TCF antagonists in clinical use. We have performed a repositioning screen for WNT-TCF response blockers aimin...

Anthelmintic resistance impact on tropical beef cattle productivity: effect on weight gain of weaned calves.

Trop. Anim. Health Prod. 45(3) , 723-7, (2013)

The performance of grazing cattle in tropical areas is deeply influenced by parasitism, and the increasing reports of resistance are a threat to effective nematode control. The present study aimed to evaluate the effect of avermectins on the performance of we...

Effects of macrocyclic lactones on the reproductive parameters of engorged Rhipicephalus (Boophilus) microplus females detached from experimentally infested cattle.

Exp. Parasitol. 135(1) , 72-8, (2013)

The present study therefore assessed the deleterious effects of MLs (ivermectin, abamectin, doramectin and moxidectin) on the reproductive parameters of engorged Rhipicephalus (Boophilus) microplus females that naturally detached from experimentally infested ...

Efficacy of monepantel, derquantel and abamectin against adult stages of a multi-resistant Haemonchus contortus isolate.

Parasitol. Res. 111(5) , 2205-7, (2012)

Drug resistance in gastrointestinal nematodes is a severe problem for sheep farmers. With the recent introduction of monepantel (Zolvix®) and of derquantel plus abamectin (Startect®) in New Zealand, two new anthelmintic classes will be available to control ga...

The role of mitochondria and biotransformation in abamectin-induced cytotoxicity in isolated rat hepatocytes.

Toxicol. In Vitro 27(2) , 570-9, (2013)

Abamectin (ABA), which belongs to the family of avermectins, is used as a parasiticide; however, ABA poisoning can impair liver function. In a previous study using isolated rat liver mitochondria, we observed that ABA inhibited the activity of adenine nucleot...

Clinical safety of rapid sequential administration of moxidectin injection and oral derquantel-abamectin as a quarantine treatment for introduced sheep.

Vet. Rec. 172(16) , 426, (2013)

Effect of abamectin exposure on semen parameters indicative of reduced sperm maturity: a study on farmworkers in Antalya (Turkey).

Andrologie 44(6) , 388-95, (2012)

Environmental exposure to pesticides may cause serious health risks including fertility and reproductive function. The aim of this study was to highlight whether there is a relationship between exposure to abamectin and male fertility parameters of farmworker...