Methyltriphenylphosphonium bromide

Methyltriphenylphosphonium bromide Structure
Methyltriphenylphosphonium bromide structure
Common Name Methyltriphenylphosphonium bromide
CAS Number 1779-49-3 Molecular Weight 357.224
Density N/A Boiling Point N/A
Molecular Formula C19H18BrP Melting Point 230-234 °C(lit.)
MSDS Chinese USA Flash Point >240°C
Symbol GHS07
GHS07
Signal Word Warning

Understanding channel blocking in the nicotinic acetylcholine receptor.

Receptors Channels 7(4) , 273-88, (2001)

Ion-channel blockers are molecules that obstruct the path used by ions to cross the membrane through a protein channel. Many of these are local anesthetics, toxins or drugs of abuse, and the knowledge of their mechanism of action at the atomic level is an imp...

Simultaneous extraction of flavonoids from Chamaecyparis obtusa using deep eutectic solvents as additives of conventional extractions solvents.

J. Chromatogr. Sci. 53 , 836-40, (2015)

Three flavones (quercetin, myricetin and amentoflavone) were extracted from Chamaecyparis obtusa leaves using deep eutectic solvents (DESs) as additives to conventional extractions solvents. Sixteen DESs were synthesized from different salts and hydrogen bond...

Primary causes of decreased mitochondrial oxygen consumption during metabolic depression in snail cells.

Am. J. Physiol. Regul. Integr. Comp. Physiol. 282(2) , R372-82, (2002)

Cells isolated from the hepatopancreas of estivating snails (Helix aspersa) have strongly depressed mitochondrial respiration compared with controls. Mitochondrial respiration was divided into substrate oxidation (which produces the mitochondrial membrane pot...

Determination of bismuth in pharmaceutical products using methyltriphenylphosphonium bromide as a molecular probe by resonance light scattering technique.

J. Pharm. Biomed. Anal. 43(3) , 1033-8, (2007)

A method for the determination of bismuth in pharmaceutical products using methyltriphenylphosphonium bromide as a molecular probe based on the resonance light scattering (RLS) technique was developed. In the presence of Tween-20, bismuth reacts with a large ...

Bioenergetic effects of mitochondrial-targeted coenzyme Q analogs in endothelial cells.

J. Pharmacol. Exp. Ther. 342(3) , 709-19, (2012)

Mitochondrial-targeted analogs of coenzyme Q (CoQ) are under development to reduce oxidative damage induced by a variety of disease states. However, there is a need to understand the bioenergetic effects of these agents and whether or not these effects are re...

Inositol trisphosphate-dependent and -independent Ca2+ mobilization pathways at the vacuolar membrane of Candida albicans.

J. Biol. Chem. 270(13) , 7272-80, (1995)

Vacuolar membrane vesicles were isolated from Candida albicans protoplasts, and marker enzyme assays were employed to identify the membranes as vacuolar in origin. The mechanisms of Ca2+ uptake and Ca2+ release at the vacuolar membrane were investigated. Ca2+...

Defective function of membrane potential (psi) on sperm of infertile men.

Arch. Androl. 38(2) , 151-5, (1997)

Membrane potential across the plasma membrane (psi) of human sperm was determined by measuring the accumulation of triphenylmethylphosphonium (TPMP+). Washed sperm of fertile or infertile men were suspended, incubated in low-K+ and high-Na+ or high-K+ and low...

Release of mitochondrial glutathione and calcium by a cyclosporin A-sensitive mechanism occurs without large amplitude swelling.

Arch. Biochem. Biophys. 315(1) , 142-52, (1994)

Treatment of isolated mitochondria with calcium and inorganic phosphate induces inner membrane permeability that is thought to be mediated through a non-selective, calcium-dependent pore. The inner membrane permeability results in the rapid efflux of small ma...

Glucose transport by mixed ruminal bacteria from a cow.

Appl. Environ. Microbiol. 63(5) , 1847-51, (1997)

The glucose transport of mixed ruminal bacteria harvested from a holstein cow fed 5.0 kg of Italian ryegrass and 1.5 kg of flaked corn a day was investigated. The Eadie-Hofstee plot characterized two transport systems: a high-affinity, low-velocity system and...

Control of oxidative phosphorylation in rat liver mitochondria: effect of ionic media.

Biochim. Biophys. Acta 1319(2-3) , 293-300, (1997)

The aim of this work was to compare oxidative phosphorylation activity and its kinetic control on isolated rat liver mitochondria in either various ionic or sucrose isoosmotic media. Whatever the ionic medium, state 3 and uncoupled state respiratory rates wer...