Azetidine hydrochloride

Azetidine hydrochloride Structure
Azetidine hydrochloride structure
Common Name Azetidine hydrochloride
CAS Number 36520-39-5 Molecular Weight 93.56
Density N/A Boiling Point 103.8ºC at 760 mmHg
Molecular Formula C3H8ClN Melting Point >300 °C(lit.)
MSDS Chinese USA Flash Point 152 °C
Symbol GHS07
GHS07
Signal Word Warning

Practical syntheses of N-substituted 3-hydroxyazetidines and 4-hydroxypiperidines by hydroxylation with Sphingomonas sp. HXN-200.

Org. Lett. 4 , 1859-1862, (2002)

[reaction: see text] Hydroxylation of N-substituted azetidines 11 and 12 and piperidines 15-19 with Sphingomonas sp. HXN-200 gave 91-98% of the corresponding 3-hydroxyazetidines 13 and 14 and 4-hydroxypiperidines 20-24, respectively, with high activity and ex...

Domino formation of enamines--intramolecular cyclizations to 1-aminotetralins from γ-arylallene aldehydes and amines.

Org. Lett. 16(20) , 5438-41, (2014)

1,5-/1,6-Allenals conjugated to an aromatic ring undergo a cyclization, in the presence of an amine, that leads to tricyclic compounds including the 1-aminotetralin scaffold. This domino process combines the in situ formation of the enamine and the cyclizatio...

Synthesis and biological evaluation of a novel phenyl substituted sydnone series as potential antitumor agents.

Bioorg. Med. Chem. Lett. 13 , 2899-2901, (2003)

A series of compounds containing an N-(4'-substituted-3'-nitrophenyl)sydnone moiety with potential antitumor activity was prepared based on active analogues. The rationale behind the design of these compounds is presented along with the 4-step synthetic route...

Synthesis of ornithine lactams via diastereoselective photocyclization of 2-amino-4-oxo-4-phenyl-butanoyl amines. Lindemann U, et al.

Tetrahedron Asymmetry 9(24) , 4459-73, (1998)