cefpodoxime

cefpodoxime Structure
cefpodoxime structure
Common Name cefpodoxime
CAS Number 80210-62-4 Molecular Weight 427.455
Density 1.8±0.1 g/cm3 Boiling Point N/A
Molecular Formula C15H17N5O6S2 Melting Point 200-202ºC
MSDS Chinese USA Flash Point N/A
Symbol GHS08
GHS08
Signal Word Danger

Isolation of Escherichia coli strains with AcrAB-TolC efflux pump-associated intermediate interpretation or resistance to fluoroquinolone, chloramphenicol and aminopenicillin from dogs admitted to a university veterinary hospital.

J. Vet. Med. Sci. 76(7) , 937-45, (2014)

Understanding the prevalence of antimicrobial-resistance and the relationship between emergence of resistant bacteria and clinical treatment can facilitate design of effective treatment strategies. We here examined antimicrobial susceptibilities of Escherichi...

Increase in resistance to extended-spectrum cephalosporins in Salmonella isolated from retail chicken products in Japan.

PLoS ONE 10(2) , e0116927, (2015)

Extended-spectrum β-lactamase (ESBL)-producing Salmonella are one of the most important public health problems in developed countries. ESBL-producing Salmonella strains have been isolated from humans in Asian countries neighboring Japan, along with strains ha...

Cephalosporinases associated with outer membrane vesicles released by Bacteroides spp. protect gut pathogens and commensals against β-lactam antibiotics.

J. Antimicrob. Chemother. 70(3) , 701-9, (2015)

To identify β-lactamase genes in gut commensal Bacteroides species and to assess the impact of these enzymes, when carried by outer membrane vesicles (OMVs), in protecting enteric pathogens and commensals.A deletion mutant of the putative class A β-lactamase ...

Oral bioavailability: issues and solutions via nanoformulations.

Clin. Pharmacokinet. 54(4) , 325-57, (2015)

The delivery of drugs through the oral route is regarded as most optimal to achieve desired therapeutic effects and patient compliance. However, poor pharmacokinetic profiles of oral drug candidates remains an area of concern, and approaches to enhance their ...

Molecular typing and genetic environment of the blaKPC gene in Chilean isolates of Klebsiella pneumoniae.

J Glob Antimicrob Resist 4 , 28-34, (2016)

The aim of this work was to determine the genetic environment and transferability of blaKPC as well as the pulsotypes of KPC-producing Klebsiella pneumoniae strains isolated from clinical samples in Chilean hospitals. Seventeen strains, principally isolated i...

Analysis of molecular epidemiologic characteristics of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli colonizing feces in hospital patients and community dwellers in a Japanese city.

J. Infect. Chemother. 22 , 102-7, (2016)

Infectious diseases caused by extended-spectrum β-lactamase (ESBL)-producing Escherichia coli are prevalent because of nosocomial infection. In addition, colonization of ESBL-producing E. coli in the intestinal tract of community dwellers due to the contamina...

Comparison of the effectiveness and safety of cefpodoxime and ciprofloxacin in acute exacerbation of chronic suppurative otitis media: A randomized, open-labeled, phase IV clinical trial.

J. Pharmacol. Pharmacother. 3 , 320-4, (2013)

To compare the effectiveness and safety of cefpodoxime and ciprofloxacin for the treatment of mild to moderate cases of acute exacerbation of chronic suppurative otitis media (AECSOM).Adult patients diagnosed with AECSOM were screened and patients fulfilling ...

Risk factors for community-acquired urinary tract infections caused by ESBL-producing enterobacteriaceae--a case-control study in a low prevalence country.

PLoS ONE 8 , e69581, (2013)

Community-acquired urinary tract infection (CA-UTI) is the most common infection caused by extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae, but the clinical epidemiology of these infections in low prevalence countries is largely unknown. A p...

An outbreak of carbapenem-resistant OXA-48 - producing Klebsiella pneumonia associated to duodenoscopy.

Antimicrob Resist Infect Control 4 , 8, (2015)

Carbapenemase-producing Enterobacteriaceae (CPE) have become a major problem for healthcare systems worldwide. While the first reports from European hospitals described the introduction of CPE from endemic countries, there is now a growing number of reports d...

A long-term low-frequency hospital outbreak of KPC-producing Klebsiella pneumoniae involving Intergenus plasmid diffusion and a persisting environmental reservoir.

PLoS ONE 8 , e59015, (2013)

To study the molecular characteristics of a long-term, low frequency outbreak of bla KPC-2 in a low prevalence setting involving the hospital environment.KPC-producing bacteria were screened by selective chromogenic agar and Real-Time PCR. The presence of ant...