Etidronate disodium
Etidronate disodium structure
|
Common Name | Etidronate disodium | ||
|---|---|---|---|---|
| CAS Number | 7414-83-7 | Molecular Weight | 249.992 | |
| Density | N/A | Boiling Point | 578.8ºC at 760 mmHg | |
| Molecular Formula | C2H6Na2O7P2 | Melting Point | > 300ºC | |
| MSDS | Chinese USA | Flash Point | 303.8ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
|
Effects of various squalene epoxides on coenzyme Q and cholesterol synthesis.
Biochim. Biophys. Acta 1841(7) , 977-86, (2014) 2,3-Oxidosqualene is an intermediate in cholesterol biosynthesis and 2,3:22,23-dioxidosqualene act as the substrate for an alternative pathway that produces 24(S),25-epoxycholesterol which effects cholesterol homeostasis. In light of our previous findings con... |
|
|
Changes in bone mineral density at 3 years in postmenopausal women receiving anastrozole and risedronate in the IBIS-II bone substudy: an international, double-blind, randomised, placebo-controlled trial.
Lancet Oncol. 15(13) , 1460-8, (2014) Aromatase inhibitors prevent breast cancer in postmenopausal women at high risk of the disease but are associated with accelerated bone loss. We assessed effectiveness of oral risedronate for prevention of reduction in bone mineral density (BMD) after 3 years... |
|
|
A novel automated hydrophilic interaction liquid chromatography method using diode-array detector/electrospray ionization tandem mass spectrometry for analysis of sodium risedronate and related degradation products in pharmaceuticals
J. Chromatogr. A. 1365 , 131-9, (2014) • HPLC fused core technology to analyze SR and its degradation products. • Stress test studies on raw material, finished products and placebos. • No interference of the complex matrices (new pharmaceuticals) was observed. • The main degradation product (SR N-... |
|
|
Risk of atypical femoral fracture during and after bisphosphonate use.
Acta Orthop. 86(1) , 100-7, (2015) Use of bisphosphonates in women is associated with higher risk of atypical femoral fractures. The risk in terms of timing of use and type of bisphosphonate, and in men, remains unclear.We reviewed radiographs of 5,342 Swedish women and men aged 55 years or mo... |
|
|
The role of risedronate in osteopenia in Crohn's disease.
Gut 64(1) , 185, (2015)
|
|
|
Etidronate disodium in the treatment of Paget's disease of bone.
Ann. Intern. Med. 96(5) , 619-25, (1982) Control of Paget's disease of bone has been possible through treatment with agents that decrease bone resorption; calcitonins, diphosphonates, and mithramycin. The pagetic lesion is not, however, cured. Etidronate disodium is one of the diphosphonates. The cl... |