pyridine oxide

pyridine oxide Structure
pyridine oxide structure
Common Name pyridine oxide
CAS Number 694-59-7 Molecular Weight 95.099
Density 1.0±0.1 g/cm3 Boiling Point 270.0±9.0 °C at 760 mmHg
Molecular Formula C5H5NO Melting Point 62-67 °C(lit.)
MSDS Chinese USA Flash Point 117.1±18.7 °C
Symbol GHS07
GHS07
Signal Word Warning

Phosphodiesterases in the rat ovary: effect of cAMP in primordial follicles.

Reproduction 150 , 11-20, (2015)

Phosphodiesterases (PDEs) are important regulators of the intracellular cAMP concentration, which is a central second messenger that affects a multitude of intracellular functions. In the ovaries, cAMP exerts diverse functions, including regulation of ovulati...

Effects of metal pyrithione antifoulants on freshwater macrophyte Lemna gibba G3 determined by image analysis.

Ecotoxicology 21(4) , 1102-11, (2012)

Copper pyrithione (CuPT(2)) and zinc pyrithione (ZnPT(2)) are two popular antifouling agents that prevent biofouling. Research into the environmental effects of metal pyrithiones has mainly focused on aquatic animal species such as fish and crustaceans, and l...

General and mild preparation of 2-aminopyridines.

Org. Lett. 12(22) , 5254-7, (2010)

A general and facile one-pot amination procedure for the synthesis of 2-aminopyridines from the corresponding pyridine-N-oxides is presented as a mild alternative to S(N)Ar chemistry. A variety of amines and heterocyclic-N-oxides participate effectively in th...

An efficient, regioselective amination of 3,5-disubstituted pyridine N-oxides using saccharin as an ammonium surrogate.

Org. Lett. 15(1) , 168-71, (2013)

A process for the regioselective amination of unsymmetrical 3,5-substituted pyridine N-oxides has been developed utilizing cheap, readily available saccharin as an ammonium surrogate. High conversions of the corresponding saccharin adducts have been achieved ...

Pyridine N-oxides as ligands in Cu-catalyzed N-arylation of imidazoles in water.

Org. Lett. 11(15) , 3294-7, (2009)

N-arylation of imidazoles with aryl halides catalyzed by a combination of copper(II) sulfate and 1,2-bis(2-pyridyl)-ethane-N,N'-dioxide in water afforded up to 95% yield.

Production of a new pyridine N-oxide by bioconversion with Cunninghamella echinulata var. elegans.

J. Biosci. Bioeng. 114(5) , 497-9, (2012)

A new N-oxide was produced from 3-(N-Boc-aminomethyl)-5-bromopyridine by bioconversion with Cunninghamella echinulata var. elegans ATCC 9245, and its structure was established based on the spectral data. The microbial N-oxidation is efficient and highly selec...

Digital pH fluorescent sensing shown by small organic molecules.

J. Fluoresc. 22(6) , 1421-4, (2012)

A series of 2-(N-oxide pyridyl)-5-methoxythiazoles were synthesized and corresponding optical properties were also investigated. It is first found that a digital-type fluorescent responses in a sharp pH variation with dual-emission could be fulfilled based on...

Pharmacokinetics of sorafenib in patients with renal impairment undergoing hemodialysis.

Int. J. Clin. Pharmacol. Ther. 47(1) , 61-4, (2009)

Pd-catalyzed oxidative CH/CH direct coupling of heterocyclic N-oxides.

Org. Lett. 15(18) , 4682-5, (2013)

A highly efficient protocol for C-H/C-H cross-coupling has been found to occur between 2-aryl-1,2,3-triazole N-oxides and pyridine N-oxide derivatives. In addition, two homocoupling reactions of 2-substituted 1,2,3-triazole N-oxides and some pyridine N-oxide ...

Palladium-catalyzed (N-oxido-2-pyridinyl)methyl transfer from 2-(2-hydroxyalkyl)pyridine N-oxide to aryl halides by beta-carbon elimination.

Chem. Asian J. 4(8) , 1217-20, (2009)