5-Carboxy-8-hydroxyquinoline
5-Carboxy-8-hydroxyquinoline structure
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Common Name | 5-Carboxy-8-hydroxyquinoline | ||
|---|---|---|---|---|
| CAS Number | 5852-78-8 | Molecular Weight | 189.167 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 464.5±30.0 °C at 760 mmHg | |
| Molecular Formula | C10H7NO3 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 234.7±24.6 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Kdm3a lysine demethylase is an Hsp90 client required for cytoskeletal rearrangements during spermatogenesis.
Mol. Biol. Cell 25(8) , 1216-33, (2014) The lysine demethylase Kdm3a (Jhdm2a, Jmjd1a) is required for male fertility, sex determination, and metabolic homeostasis through its nuclear role in chromatin remodeling. Many histone-modifying enzymes have additional nonhistone substrates, as well as nonen... |
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IOX1, a JMJD2A inhibitor, suppresses the proliferation and migration of vascular smooth muscle cells induced by angiotensin II by regulating the expression of cell cycle-related proteins.
Int. J. Mol. Med. 37 , 189-96, (2015) The epigenetic modification of vascular smooth muscle cell (VSMC) phenotypic switching, proliferation, migration, apoptosis and extracellular matrix synthesis is known to occur in atherosclerosis. The aim of the present study was to investigate the effects of... |
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A scintillation proximity assay for histone demethylases.
Anal. Biochem. 463 , 54-60, (2014) Covalent modifications, such as methylation and demethylation of lysine residues in histones, play important roles in chromatin dynamics and the regulation of gene expression. The lysine demethylases (KDMs) catalyze the demethylation of lysine residues on his... |