Tinidazole

Tinidazole Structure
Tinidazole structure
Common Name Tinidazole
CAS Number 19387-91-8 Molecular Weight 247.271
Density 1.4±0.1 g/cm3 Boiling Point 528.4±30.0 °C at 760 mmHg
Molecular Formula C8H13N3O4S Melting Point 117-121 °C(lit.)
MSDS Chinese USA Flash Point 273.4±24.6 °C
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Warning

Simultaneous determination of 15 nitroimidazoles in cosmetics by HPLC coupled with electrospray ionization- tandem mass spectrometry.

J. AOAC Int. 97(6) , 1538-45, (2015)

A sensitive and reliable analytical method based on HPLC/MSIMS has been developed for the simultaneous determination of 15 nitroimidazoles in cosmetics. A diversity of cosmetic samples, including powder, lotion, shampoo, and cream were collected. The samples ...

A comparative study of sequential therapy and standard triple therapy for Helicobacter pylori infection: a randomized multicenter trial.

Am. J. Gastroenterol. 109(4) , 535-41, (2014)

Studies conducted in large populations of patients and providing full information on Helicobacter pylori (H. pylori) antibiotic resistance are needed to determine the efficacy of sequential therapy (SQT) against this pathogen. This study compared eradication ...

Phenotypic and transcriptional profiling in Entamoeba histolytica reveal costs to fitness and adaptive responses associated with metronidazole resistance.

Front. Microbiol. 6 , 354, (2015)

Antimicrobial chemotherapy is critical in the fight against infectious diseases caused by Entamoeba histolytica. Among the drugs available for the treatment of amebiasis, metronidazole (MTZ) is considered the drug of choice. Recently, in vitro studies have de...

Seminal Helicobacter pylori treatment improves sperm motility in infertile asthenozoospermic men.

Urology 84(6) , 1347-50, (2014)

To assess the effect of treatment of seminal Helicobacter pylori in infertile asthenozoospermic men.In all, 223 infertile asthenozoospermic men were consecutively selected. They were subjected to history taking, clinical examination, semen analysis, and estim...

A novel method for tinidazole detection using Mn-modified CdSe/CdS quantum dots as a luminescent probe.

J. Nanosci. Nanotechnol. 14(5) , 3976-82, (2014)

A new method for the determination of tinidazole based on the fluorescence quenching of citrate-capped Mn-modified CdSe/CdS quantum dots was developed. In aqueous solution, the fluorescence of the quantum dots at 610 nm was quenched gradually with the increas...

Extractional spectrophotometric analysis of metronidazole, tinidazole, ornidazole and secnidazole bases through acid-dye complexation using bromothymol blue dye.

Pak. J. Pharm. Sci. 25(1) , 207-17, (2012)

An easy, precise and valid extractional-spectrophotometric technique is described for the assessment of metronidazole (MNZ), tinidazole (TNZ), ornidazole (ONZ) and secnidazole (SNZ) in pure state and in their pharmaceutical formulations. The technique include...

Part XI. Trimethoprim-sulfamethoxazole, nitrofurantoin, chloramphenicol, metronidazole and tinidazole, rifaximin, and nitazoxanide.

J. Okla. State Med. Assoc. 100(7) , 267-72, (2007)

An integrated microfludic device for culturing and screening of Giardia lamblia.

Exp. Parasitol. 137 , 1-7, (2014)

In vitro culturing of trophozoites was important for research of Giardia lamblia (G. lamblia), especially in discovery of anti-Giardia agents. The current culture methods mainly suffer from lab-intension or the obstacle in standardizing the gas condition. Thu...

Drugs for treating giardiasis.

Cochrane Database Syst. Rev. 12 , CD007787, (2012)

Giardiasis infection may be asymptomatic, or can cause diarrhoea (sometimes severe), weight loss, malabsorption, and, in children, failure to thrive. It is usually treated with metronidazole given three times daily for five to 10 days.To evaluate the relative...

Increased protein carbonylation and decreased antioxidant status in anemic H. pylori infected patients: effect of treatment.

Saudi J. Gastroenterol. 18(4) , 252-6, (2012)

Collective evidences suggest the causal association of Helicobacter pylori infection with iron deficiency anemia. Generation of free radicals against this bacterium can lead to turbulence in oxidative-antioxidative system. This study was undertaken to evaluat...