![]() Terazosin structure
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Common Name | Terazosin | ||
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CAS Number | 63590-64-7 | Molecular Weight | 387.43300 | |
Density | 1.332 g/cm3 | Boiling Point | 664.5ºC at 760 mmHg | |
Molecular Formula | C19H25N5O4 | Melting Point | 281-283°C | |
MSDS | Chinese USA | Flash Point | 355.7ºC | |
Symbol |
![]() GHS07 |
Signal Word | Warning |
Noradrenergic modulation of masseter muscle activity during natural rapid eye movement sleep requires glutamatergic signalling at the trigeminal motor nucleus.
J. Physiol. 592(Pt 16) , 3597-609, (2014) Noradrenergic neurotransmission in the brainstem is closely coupled to changes in muscle activity across the sleep-wake cycle, and noradrenaline is considered to be a key excitatory neuromodulator that reinforces the arousal-related stimulus on motoneurons to... |
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Method development for impurity profiling in SFC: The selection of a dissimilar set of stationary phases.
J. Pharm. Biomed. Anal. 111 , 333-43, (2015) Supercritical fluid chromatography (SFC) is drawing considerable interest as separation technique in the pharmaceutical industry. The technique is already well established in chiral separations both analytically and on a preparative scale. The use of SFC as a... |
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Efficacy of three different alpha 1-adrenergic blockers and hyoscine N-butylbromide for distal ureteral stones.
Int. Braz J Urol 37(2) , 195-200; discussion 201-2, (2011) To evaluate hyoscine N-butyl bromide (HBB) and three different alpha-1 blockers in the treatment of distal ureteral stones.A total of 140 patients with stones located in the distal tract of the ureter with stone diameters of 5 to 10mm were enrolled in the pre... |
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Multiple cerebral infarctions related to famotidine-induced eosinophilia.
J. Neurol. 259(10) , 2229-31, (2012)
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Pharmacologic pupil dilation as a predictive test for the risk for intraoperative floppy-iris syndrome.
J. Cataract Refract. Surg. 37(8) , 1447-54, (2011) To evaluate the effect of α1-adrenergic receptor antagonists (α1-ARAs) on pupil diameter and determine whether the diameter predicts intraoperative floppy-iris syndrome (IFIS).Ophthalmology Section, Palermo University, Palermo, Italy.Prospective cohort study.... |
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[How effective is finasteride?].
Dtsch. Med. Wochenschr. 136(8) , 354, (2011)
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Terazosin activates Pgk1 and Hsp90 to promote stress resistance.
Nat. Chem. Biol. 11(1) , 19-25, (2015) Drugs that can protect against organ damage are urgently needed, especially for diseases such as sepsis and brain stroke. We discovered that terazosin (TZ), a widely marketed α1-adrenergic receptor antagonist, alleviated organ damage and improved survival in ... |
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[Efficacy of compound Xuanju capsule in the treatment of chronic prostatitis with erectile dysfunction].
Zhonghua Nan Ke Xue 18(10) , 950-2, (2012) To evaluate the efficacy and safety of Compound Xuanju Capsule (CXC) in the treatment of chronic prostatitis with erectile dysfunction (ED).We obtained NIH-CPSI and IIEF-5 scores from 132 chronic prostatitis patients with ED and divided the patients into a co... |
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An alpha1-adrenoceptor blocker terazosin improves urine storage function in the spinal cord in spinal cord injured rats.
Life Sci. 92(2) , 125-30, (2013) To confirm the role of alpha1-adrenoceptor (α(1)-AR) in the spinal cord, we investigated the effect of intrathecal application of terazosin, a non-selective α(1)-AR blocker, on the micturition reflex, as well as the change of α(1)-AR subtypes mRNA in the lumb... |
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Effect of terazosin on sweating in patients with major depressive disorder receiving sertraline: a randomized controlled trial.
Int. J. Psychiatry Clin. Pract. 17(1) , 44-7, (2013) By considering the role of adrenergic nervous system in sweat secretion, we postulated that terazosin may be able to improve sweating after taking sertraline, a selective serotonin reuptake inhibitor (SSRI) drug. This study was designed to evaluate the effect... |