2-Naphthol
2-Naphthol structure
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Common Name | 2-Naphthol | ||
|---|---|---|---|---|
| CAS Number | 135-19-3 | Molecular Weight | 144.170 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 285.5±0.0 °C at 760 mmHg | |
| Molecular Formula | C10H8O | Melting Point | 120-122 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 144.0±10.6 °C | |
| Symbol |
GHS07, GHS09 |
Signal Word | Warning | |
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High-performance thin-layer chromatography analysis of steviol glycosides in Stevia formulations and sugar-free food products, and benchmarking with (ultra) high-performance liquid chromatography.
J. Chromatogr. A. 1350 , 102-11, (2014) A high-performance TLC (HPTLC) method was newly developed and validated for analysis of 7 steviol glycosides in 6 different types of food and Stevia formulations. After a minimized one-step sample preparation, 21 samples were developed in parallel, allowing a... |
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Development of a novel magnetic molecularly imprinted polymer coating using porous zeolite imidazolate framework-8 coated magnetic iron oxide as carrier for automated solid phase microextraction of estrogens in fish and pork samples.
J. Chromatogr. A. 1365 , 35-44, (2014) A high-performance magnetic molecularly imprinted polymer (MIP) coating using zeolite imidazolate framework-8 coated magnetic iron oxide (Fe3O4@ZIF-8) as a carrier was developed for simultaneous automated solid phase microextraction of four estrogens in 24 fo... |
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QSAR study and synthesis of new phenyltropanes as ligands of the dopamine transporter (DAT).
Bioorg. Med. Chem. 20 , 1388-95, (2012) The dopamine transporter (DAT) plays a pivotal role in the regulation of dopamine neurotransmission, and is involved in a number of physiological functions and brain disorders. Furthermore the DAT analysis by molecular imaging techniques is a useful tool for ... |
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Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
J. Med. Chem. 48 , 3269-79, (2005) Growing interest in the use of both the logarithm of the partition coefficient of the neutral species in the alkane/water system (log P(N)(alk)) and the difference between log P(N)(oct) (the logarithm of the partition coefficient of the neutral species in the... |
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Preparation and evaluation of benzyl methacrylate monoliths for capillary chromatography.
J. Chromatogr. Sci. 52(3) , 201-10, (2014) This paper describes the comprehensive fabrication of monolithic materials for use as stationary phases in capillary liquid chromatography. Several columns were synthesized in the confines of 320 µm i.d. fused-silica capillaries by single-step in situ copolym... |
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Condensation of 2-naphthol and naphthalenediols with o-dichlorobenzene in the presence of aluminum halides.
Chem. Pharm. Bull. 60(6) , 722-7, (2012) It is known that 1-naphthol, as a result of superelectrophilic (dicationic) activation in superacid media, is able to react with such deactivated aromatic compound as o-dichlorobenzene to give 4-(3,4-dichlorophenyl)-1-tetralone (2), which is a highly valuable... |
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Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Bioorg. Med. Chem. 15 , 6943-55, (2007) A set of 116 structurally very diverse compounds, mainly drugs, was characterized by 1630 molecular descriptors. The biological property modelled in this study was the transdermal permeability coefficient logK(p). The main objective was to find a limited set ... |
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Detection of polycyclic aromatic hydrocarbons (PAHs) in raw menhaden fish oil using fluorescence spectroscopy: Method development.
Environ. Toxicol. Chem. 34 , 1946-58, (2015) Raw menhaden fish oil was developed for biomonitoring polycyclic aromatic hydrocarbons (PAHs) using fluorescence spectroscopy. Menhaden (Genus Brevoortia) were collected in 2010 and/or 2011 from Delaware Bay, New Jersey, USA; James River, Virginia, USA; Vermi... |
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Parallel artificial membrane permeability assay: a new membrane for the fast prediction of passive human skin permeability.
J. Med. Chem. 49 , 3948-54, (2006) This work was devoted to the search for new artificial membranes allowing a rapid evaluation of passive human skin permeation of compounds with a parallel artificial membrane permeability assay (PAMPA). Effective permeability coefficients (Pe) determined for ... |
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In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities.
J. Med. Chem. 50 , 742-8, (2007) The development of in silico and in vitro tools to estimate or predict the passive human skin permeation and distribution of new chemical entities, useful in dermal drug delivery, in absorption studies of toxic compounds, and in the cosmetics industry, is pre... |