Bikaverin

Bikaverin Structure
Bikaverin structure
Common Name Bikaverin
CAS Number 33390-21-5 Molecular Weight 382.32000
Density 1.61g/cm3 Boiling Point 719.8ºC at 760mmHg
Molecular Formula C20H14O8 Melting Point N/A
MSDS Chinese USA Flash Point 263.3ºC
Symbol GHS06
GHS06
Signal Word Danger

Bikaverin and fusaric acid from Fusarium oxysporum show antioomycete activity against Phytophthora infestans.

J. Appl. Microbiol. 104(3) , 692-8, (2008)

To isolate and identify antioomycete substances from Fusarium oxysporum EF119 against Phytophthora infestans and to investigate their antimicrobial activities against various plant pathogenic bacteria, oomycetes and true fungi.Two antioomycete substances were...

United States Department of Agriculture-Agricultural Research Service studies on polyketide toxins of Fusarium oxysporum f sp vasinfectum: potential targets for disease control.

Pest Manag. Sci. 59(6-7) , 736-47, (2003)

A group of 133 isolates of the cotton wilt pathogen Fusarium oxysporum Schlecht f sp vasinfectum (Atk) Sny & Hans, representing five races and 20 vegetative compatibility groups within race 1 were used to determine the identity, biosynthetic regulation and ta...

GAC1, a gene encoding a putative GTPase-activating protein, regulates bikaverin biosynthesis in Fusarium verticillioides.

Mycologia 100(5) , 701-9, (2008)

Fusarium verticillioides (teleomorph Gibberella moniliformis) is an ascomycete known to produce a variety of secondary metabolites, including fumonisins, fusaric acid and bikaverin. These metabolites are synthesized when the fungus is under stress, notably nu...

Stimulation of bikaverin production by sucrose and by salt starvation in Fusarium fujikuroi.

Appl. Microbiol. Biotechnol. 85(6) , 1991-2000, (2010)

The fungus Fusarium fujikuroi (Gibberella fujikuroi mating group C) exhibits a rich secondary metabolism that includes the synthesis of compounds of biotechnological interest, such as gibberellins, bikaverin, and carotenoids. The effect of the carbon source o...

FUMandBIKgene expression contribute to describe fumonisin and bikaverin synthesis inFusarium verticillioides

Int. J. Food Microbiol. 160(2) , 94-8, (2012)

Fusarium verticillioides is a maize pathogen that produces toxic secondary metabolites, including fumonisins and bikaverin. The regulation of biosynthetic gene expression and the production of these metabolites are not fully understood and in this study we in...

LC-MS/MS method for the determination of the fungal pigment bikaverin in maize kernels as an indicator of ear rot.

Food Addit. Contam. Part A. Chem. Anal. Control. Expo. Risk Assess. 29(11) , 1736-42, (2012)

Bikaverin is a polyketide-derived pigment produced by multiple species of the fungus Fusarium, some of which can cause ear and kernel rot of maize. A method was developed for the analysis of bikaverin by high-performance liquid chromatography (LC) coupled to ...

A comprehensive overview on genomically directed assembly of aromatic polyketides and macrolide lactones using fungal megasynthases.

J. Antibiot. 64(1) , 9-17, (2011)

Fungal polyketide synthases (PKSs) catalyze a carbon-carbon bond forming reaction in an iterative manner using a variety of acyl-CoA molecules as substrates when biosynthesizing complex polyketides. Although most members from this class of natural products ex...

Aeration affects acetate destination in Gibberella fujikuroi.

FEMS Microbiol. Lett. 180(1) , 111-6, (1999)

Gibberellins, fatty acids and the polyketides bikaverin and fusarin C are synthesized from a common precursor, acetyl-CoA. The production of these compounds in Gibberella fujikuroi was strongly influenced by aeration, determined by the air/medium ratio in sha...

Purpurin as a specific inhibitor of spermidine-induced autoactivation of the protease plasma hyaluronan-binding protein.

Biol. Pharm. Bull. 33(8) , 1430-3, (2010)

Plasma hyaluronan-binding protein (PHBP), a serine protease that can activate coagulation factor VII and prourokinase, circulates as a single-chain form (pro-PHBP), and is autoproteolytically converted to an active two-chain form with the aid of an effector s...

Characterization of antibacterial activity of bikaverin from Fusarium sp. HKF15.

J. Biosci. Bioeng. 117(4) , 443-8, (2014)

Redeemed interest in discovery and characterization of naturally occurring antimicrobials arises from the fact that these compounds possess diverse biological activities useful in the development of new therapeutics. In this study, 35 fungi from extreme envir...