Mcl1-IN-11

Modify Date: 2024-01-13 16:46:24

Use of Mcl1-IN-11

Mcl1-IN-11 (Compound G) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.06 and 4.2 μM, respectively[1].

Name	Mcl1-IN-11

Description	Mcl1-IN-11 (Compound G) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.06 and 4.2 μM, respectively[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Bcl-2 Family Research Areas >> Cancer
Target	Ki: 0.06 (Mcl-1), 4.2 μM (Bcl-2)[1]
References	[1]. Wang M, et al. Design, synthesis, and activity evaluation of selective inhibitors of anti-apoptotic Bcl-2 proteins: The effects on the selectivity of the P1 pockets in the active sites. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5207-5211.

Molecular Formula	C₃₈H₄₁N₃O₅S₂
Molecular Weight	683.88