Name | [(5S,6R,8S,8aR)-5-(2-acetyloxypropan-2-yl)-3,8-dimethyl-2-oxo-4,5,6,7,8,8a-hexahydro-1H-azulen-6-yl] (Z)-2-methylbut-2-enoate |
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Synonyms |
2-Butenoic acid, 2-methyl-, (3aR,4S,6R,7S)-7-[1-(acetyloxy)-1-methylethyl]-2,3,3a,4,5,6,7,8-octahydro-1,4-dimethyl-2-oxo-6-azulenyl ester, (2Z)-
8-angeloyl-11-acetyl-8,11-dihydroxy-4-guaien-3-one (5S,6R,8S,8aR)-5-(2-Acetoxy-2-propanyl)-3,8-dimethyl-2-oxo-1,2,4,5,6,7,8,8a-octahydro-6-azulenyl (2Z)-2-methyl-2-butenoate torilin 11-acetoxy-8-angeloyl-4-guaien-3-one |
Description | Torilin is a sesquiterpene with antimicrobial, anticancer, and anti-inflammatory properties. Torilin inhibits LPS-induced NO release, as well as inhibiting iNOS, PGE2, COX-2, NF-α, IL-1β, IL-6, and GM-CSF. Torilin suppresses NF-kB and AP-1 translocation, inhibits TAK1 kinase activation. Subsequently results suppression of MAPK-mediated JNK, p38, ERK1/2, and AP-1 (ATF-2 and c-jun) activation and IKK-mediated I-κBα degradation, p65/p50 activation, and translocation[1]. |
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Related Catalog | |
References |
Density | 1.1±0.1 g/cm3 |
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Boiling Point | 469.2±45.0 °C at 760 mmHg |
Melting Point | 78-79℃ (methanol ) |
Molecular Formula | C22H32O5 |
Molecular Weight | 376.49 |
Flash Point | 201.0±28.8 °C |
Exact Mass | 376.224976 |
PSA | 69.67000 |
LogP | 4.23 |
Vapour Pressure | 0.0±1.2 mmHg at 25°C |
Index of Refraction | 1.508 |
Hazard Codes | Xi |
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