327-97-9

327-97-9 structure

Name: Chlorogenic acid
Chemical Name: chlorogenic acid
CAS Number: 327-97-9
Molecular Formula: C₁₆H₁₈O₉
Molecular Weight: 354.309
Catalog: API Antipyretic analgesics Antipyretic and analgesic
Create Date: 2018-02-03 08:00:00
Modify Date: 2025-08-21 19:23:49
Chlorogenic acid is a major phenolic compound in coffee and tea. It plays several important and therapeutic roles such as antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension.

Name	chlorogenic acid
Synonyms	Hlorogenic acid Chlorogenic Acid Hydrate Caffeoyl quinic acid Chlorogenate (1S,3R,4R,5R)-3-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy-1,4,5-trihydroxycyclohexane-1-carboxylic acid 3-Caffeoylquinate 5-caffeoylquinic acid 3-O-Caffeoylquinic acid 3-Caffeoylquinic acid CHLOROGENIC ACID Chlorogenic acid,predominantly trans,from coffee seeds 3-(3,4-Dihydroxycinnamoyl)quinic Acid Hydrate Heriguard EINECS 206-325-6 3-mono-O-caffeoylquinic acid MFCD00003862

Description	Chlorogenic acid is a major phenolic compound in coffee and tea. It plays several important and therapeutic roles such as antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension.
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> HIF/HIF Prolyl-Hydroxylase Research Areas >> Inflammation/Immunology Natural Products >> Phenylpropanoids
References	[1]. Park JJ, et al. Chlorogenic acid inhibits hypoxia-induced angiogenesis via down-regulation of the HIF-1α/AKT pathway. Cell Oncol (Dordr). 2015 Jan 6. [2]. Park SH, et al. IRAK4 as a Molecular Target in the Amelioration of Innate Immunity-Related Endotoxic Shock and Acute Liver Injury by Chlorogenic Acid. J Immunol. 2015 Feb 1;194(3):1122-30. [3]. Kang JW, et al. Protective Effects of Chlorogenic Acid against Experimental Reflux Esophagitis in Rats. Biomol Ther (Seoul). 2014 Sep;22(5):420-5.

CHEMICAL NAME :: Cyclohexanecarboxylic acid, 3-((3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl)oxy)- 1,4,5-trihydroxy-, (1S-(1-alpha,3-beta,4-alpha,5-alpha))-

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - musculoskeletal system

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 111,209,1983

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi: Irritant;
Risk Phrases	R68
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	GU8480000