BioBioPha
China
Product Name: Crocin 1
Price: ￥Inquiry/5mg
Purity: 98.0%
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Crocin
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DC Chemicals Limited
China
Product Name: CROCIN
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Zhejiang Hangyu API Co., Ltd
China
Product Name: CROCIN
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Henan Tianfu Chemical Co., Ltd.
China
Product Name: CROCIN 42553-65-1
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Purity: 99.0%
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Contact: Anson

42553-65-1

42553-65-1 structure

42553-65-1 structure

Name: Crocin
Chemical Name: Crocin (Gardenia Fruits Extract)
CAS Number: 42553-65-1
Molecular Formula: C₄₄H₆₄O₂₄
Molecular Weight: 976.965
Catalog: Food additive Color protection agent
Create Date: 2018-10-04 14:16:25
Modify Date: 2024-01-05 10:24:14
Crocin is a nutraceutical and the main constituent isolated from the stigmas of Crocus sativus with immense pharmacological properties as anti-inflammatory, anticancer, antidepressant and anticonvulsant[1].

Name	Crocin (Gardenia Fruits Extract)
Synonyms	Crocetin digentiobiose ester Bis[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}methyl)tetrahydro-2H-pyran-2-yl] (2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-tetramethyl-2,4,6,8,10,12,14-hexadecaheptaenedioate EINECS 255-881-6 MFCD00017495 Bis[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}methyl)tetrahydro-2H-pyran-2-yl] (2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-tetramethylhexadeca-2,4,6,8,10,12,14-heptaenedioate (non-preferred name) CROCIN 8,8'-Diapo-y,y-carotenedioic acid bis(6-O-b-D-glucopyranosyl-b-D-glucopyranosyl) ester Digentiobiosyl 8,8'-Diapo-8,8'-carotenedioate Crocetin Digentiobiosyl Ester (Gardenia Fruits Extract) a-Crocin Bis[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}methyl)tetrahydro-2H-pyran-2-yl] (2E,4E,6E,8E,10E,12E,14E)-2,6,11,15-tetramethyl-2,4,6,8,10,12,14-hexadecaheptaenedioate (non-preferred name) Crocetin Digentiobiosyl Ester Crocin 1

Description	Crocin is a nutraceutical and the main constituent isolated from the stigmas of Crocus sativus with immense pharmacological properties as anti-inflammatory, anticancer, antidepressant and anticonvulsant[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease
References	[1]. Zaghloul MS, et al. Crocin attenuates lung inflammation and pulmonary vascular dysfunction in a rat model of bleomycin-induced pulmonary fibrosis. Life Sci. 2019 Aug 26:116794.

Density	1.5±0.1 g/cm3
Boiling Point	1169.0±65.0 °C at 760 mmHg
Melting Point	186° (effervescence)
Molecular Formula	C₄₄H₆₄O₂₄
Molecular Weight	976.965
Flash Point	337.8±27.8 °C
Exact Mass	976.378723
PSA	391.20000
LogP	-0.83
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.650
Storage condition	2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HL7380000

CHEMICAL NAME :: 8,8'-Diapo-psi,psi-carotenedioic acid, bis(6-O-beta-D-glucopyranosyl-beta-D- glucopyranosyl) ester

CAS REGISTRY NUMBER :: 42553-65-1

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C44-H64-O24

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 10 gm/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - altered sleep time (including change in righting reflex) Behavioral - changes in motor activity (specific assay)

REFERENCE :: JJPAAZ Japanese Journal of Pharmacology. (Japanese Pharmacological Soc., c/o Dept. of Pharmacology, Faculty of Medicine, Kyoto Univ., Sakyo-ku, Kyoto 606, Japan) V.1- 1951- Volume(issue)/page/year: 4,69,1954

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
Safety Phrases	24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	HL7380000
HS Code	32129000

42553-65-1 structure

42553-65-1

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42553-65-1 structure

42553-65-1

Literature: Speranza, Giovanna; Dada, Giuseppe; Manitto, Paolo; Monti, Diego; Gramatica, Paola Gazzetta Chimica Italiana, 1984 , vol. 114, # 3/4 p. 189 - 192

Precursor 1
42553-65-1
DownStream 2
42553-65-1 27876-94-4