Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Palmitic acid
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

176591-49-4

176591-49-4 structure

176591-49-4 structure

Name: Urocortin human
Chemical Name: Urocortin, human
CAS Number: 176591-49-4
Molecular Formula: C₂₀₄H₃₃₇N₆₃O₆₄
Molecular Weight: 4696.24
Catalog: Peptides
Create Date: 2018-02-28 21:27:59
Modify Date: 2026-07-07 20:54:57
Urocortin, human, a 40-aa neuropeptide, acts as a selective agonist of endogenous CRF2 receptor, with Kis of 0.4, 0.3, and 0.5 nM for hCRF1, rCRF2α and mCRF2β, respectively.

Name	Urocortin, human
Synonyms	Urocortin human >= (HPLC), powder Urocortin (human) (9CI) urocortin H-ASP-ASN-PRO-SER-LEU-SER-ILE-ASP-LEU-THR-PHE-HIS-LEU-LEU-G-THR-LEU-LEU-GLU-LEU-ALA-G-THR-GLN-SER-GLN-G-GLU-G-ALA-GLU-GLN-ASN-G-ILE-ILE-PHE-ASP-SER-VAL-NH2 Human urocortin I C204H337N63O64 Anti-Urocortin, C-Terminal antibody produced in rabbit Human urocortin 1 UROCORTIN (HUMAN) Human urocortin Urocortin huManUrocortin h UROCORTIN (HUMAN) TRIFLUOROACETATE SALT Urocortin 1 (human) Urocortin human, (HPLC) MFCD00802621 H-Asp-Asn-Pro-Ser-Leu-Ser-Ile-Asp-Leu-Thr-Phe-His-Leu-Leu-g-Thr-Leu-Leu-Glu-Leu-Ala-g-Thr-Gln-Ser-Gln-gGlu-g-Ala-Glu-Gln-Asn-g-Ile-Ile-Phe-Asp-Ser-Val-NH2 ASP-ASN-PRO-SER-LEU-SER-ILE-ASP-LEU-THR-PHE-HIS-LEU-LEU-G-THR-LEU-LEU-GLU-LEU-ALA-G-THR-GLN-SER-GLN-G-GLU-G-ALA-GLU-GLN-ASN-G-ILE-ILE-PHE-ASP-SER-VAL-NH2

Description	Urocortin, human, a 40-aa neuropeptide, acts as a selective agonist of endogenous CRF2 receptor, with Kis of 0.4, 0.3, and 0.5 nM for hCRF1, rCRF2α and mCRF2β, respectively.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> CRFR Peptides Research Areas >> Neurological Disease
Target	Ki: 0.4 nM (hCRF1, cell assay), 0.3 nM (rCRF2α, cell assay), and 0.5 nM (mCRF2β, cell assay)[1]
In Vitro	Urocortin, human is a selective agonist of CRF2 receptor, with Kis of 0.4, 0.3, and 0.5 nM for human CRF1, rat CRF2α and mouse CRF2β receptors in cell assay, respectively[1].
In Vivo	Urocortin (0.01 to 10 μg) decreases food intake in both food-deprived and non-deprived rats and such a effect also observed in mice after 1 μg of Urocortin i.c.v. administration. Urocortin has the potential of inducing anxiogenic behavior[2].
References	[1]. Reul JM, et al. Corticotropin-releasing factor receptors 1 and 2 in anxiety and depression. Curr Opin Pharmacol. 2002 Feb;2(1):23-33. [2]. Skelton KH, et al. The neurobiology of urocortin. Regul Pept. 2000 Sep 25;93(1-3):85-92.

Molecular Formula	C₂₀₄H₃₃₇N₆₃O₆₄
Molecular Weight	4696.24
Storage condition	-20°C

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
RIDADR	NONH for all modes of transport
WGK Germany	3.0

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.