2248702-80-7

2248702-80-7 structure
2248702-80-7 structure
  • Name: TDP1 Inhibitor-1
  • Chemical Name: TDP1 Inhibitor-1
  • CAS Number: 2248702-80-7
  • Molecular Formula: C26H26N2O5
  • Molecular Weight: 446.50
  • Catalog: Research Areas Cancer
  • Create Date: 2019-06-29 22:02:33
  • Modify Date: 2024-01-10 18:53:52
  • TDP1 Inhibitor-1 is a potent Tyrosyl-DNA Phosphodiesterase 1 (TDP1) inhibitor with an IC50 of 7 μM[1].

Name TDP1 Inhibitor-1
Description TDP1 Inhibitor-1 is a potent Tyrosyl-DNA Phosphodiesterase 1 (TDP1) inhibitor with an IC50 of 7 μM[1].
Related Catalog
Target

IC50: 7 μM (Tyrosyl-DNA Phosphodiesterase 1)[1]

References

[1]. Zhang XR, et al. Discovery, Synthesis, and Evaluation of Oxynitidine Derivatives as Dual Inhibitors of DNA Topoisomerase IB (TOP1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1), and Potential Antitumor Agents. J Med Chem. 2018 Nov 21;61(22):9908-9930.

Molecular Formula C26H26N2O5
Molecular Weight 446.50
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