TDP1 Inhibitor-1

Modify Date: 2024-01-10 18:53:52

TDP1 Inhibitor-1 Structure
TDP1 Inhibitor-1 structure
 Common Name TDP1 Inhibitor-1
CAS Number 2248702-80-7 Molecular Weight 446.50
Density N/A Boiling Point N/A
Molecular Formula C26H26N2O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TDP1 Inhibitor-1


TDP1 Inhibitor-1 is a potent Tyrosyl-DNA Phosphodiesterase 1 (TDP1) inhibitor with an IC50 of 7 μM[1].

 Names

Name TDP1 Inhibitor-1

 TDP1 Inhibitor-1 Biological Activity

Description TDP1 Inhibitor-1 is a potent Tyrosyl-DNA Phosphodiesterase 1 (TDP1) inhibitor with an IC50 of 7 μM[1].
Related Catalog
Target

IC50: 7 μM (Tyrosyl-DNA Phosphodiesterase 1)[1]

References

[1]. Zhang XR, et al. Discovery, Synthesis, and Evaluation of Oxynitidine Derivatives as Dual Inhibitors of DNA Topoisomerase IB (TOP1) and Tyrosyl-DNA Phosphodiesterase 1 (TDP1), and Potential Antitumor Agents. J Med Chem. 2018 Nov 21;61(22):9908-9930.

 Chemical & Physical Properties

Molecular Formula C26H26N2O5
Molecular Weight 446.50
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