2055024-45-6

2055024-45-6 structure

2055024-45-6 structure

Name: Azide-PEG3-Sulfone-PEG3-azide
Chemical Name: Azide-PEG3-Sulfone-PEG3-azide
CAS Number: 2055024-45-6
Molecular Formula: C₁₆H₃₂N₆O₈S
Molecular Weight: 468.53
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 20:20:33
Modify Date: 2024-01-16 08:30:18
Azide-PEG3-Sulfone-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Azide-PEG3-Sulfone-PEG3-azide

Description	Azide-PEG3-Sulfone-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₆H₃₂N₆O₈S
Molecular Weight	468.53