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54149-49-4

54149-49-4 structure
54149-49-4 structure
  • Name: Aminooxy-PEG2-methane
  • Chemical Name: m-PEG2-Amino
  • CAS Number: 54149-49-4
  • Molecular Formula: C5H13NO3
  • Molecular Weight: 135.16
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-01 12:04:11
  • Modify Date: 2024-01-09 17:44:32
  • m-PEG2-Amino is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name m-PEG2-Amino
Description m-PEG2-Amino is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C5H13NO3
Molecular Weight 135.16