Aminooxy-PEG2-methane

Modify Date: 2024-01-09 17:44:32

Aminooxy-PEG2-methane Structure
Aminooxy-PEG2-methane structure
Common Name Aminooxy-PEG2-methane
CAS Number 54149-49-4 Molecular Weight 135.16
Density N/A Boiling Point N/A
Molecular Formula C5H13NO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Aminooxy-PEG2-methane


m-PEG2-Amino is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name m-PEG2-Amino

 Aminooxy-PEG2-methane Biological Activity

Description m-PEG2-Amino is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C5H13NO3
Molecular Weight 135.16
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