Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Mal-NH-PEG4-CH2CH2COOPFP ester
Price:
Purity: 97.0%
Stocking Period: 10 Day
Contact: Huang

1347750-84-8

1347750-84-8 structure

1347750-84-8 structure

Name: Mal-NH-PEG4-CH2CH2COOPFP ester
Chemical Name: Mal-NH-PEG4-CH2CH2COOPFP ester
CAS Number: 1347750-84-8
Molecular Formula: C₂₄H₂₇F₅N₂O₉
Molecular Weight: 582.47
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 21:13:55
Modify Date: 2024-01-30 09:57:55
Mal-NH-PEG4-CH2CH2COOPFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Mal-NH-PEG4-CH2CH2COOPFP ester
Synonyms	MFCD28899322

Description	Mal-NH-PEG4-CH2CH2COOPFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₂₄H₂₇F₅N₂O₉
Molecular Weight	582.47

Hazard Codes	Xi