2353409-49-9

2353409-49-9 structure

2353409-49-9 structure

Name: Methyltetrazine-PEG8-PFP ester
Chemical Name: Methyltetrazine-PEG8-PFP ester
CAS Number: 2353409-49-9
Molecular Formula: C₃₄H₄₃F₅N₄O₁₁
Molecular Weight: 778.72
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-02 05:12:08
Modify Date: 2024-01-04 14:38:22
Methyltetrazine-PEG8-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Methyltetrazine-PEG8-PFP ester

Description	Methyltetrazine-PEG8-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₃₄H₄₃F₅N₄O₁₁
Molecular Weight	778.72