2353409-49-9

2353409-49-9 structure
2353409-49-9 structure
  • Name: Methyltetrazine-PEG8-PFP ester
  • Chemical Name: Methyltetrazine-PEG8-PFP ester
  • CAS Number: 2353409-49-9
  • Molecular Formula: C34H43F5N4O11
  • Molecular Weight: 778.72
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-06-02 05:12:08
  • Modify Date: 2024-01-04 14:38:22
  • Methyltetrazine-PEG8-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Methyltetrazine-PEG8-PFP ester
Description Methyltetrazine-PEG8-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C34H43F5N4O11
Molecular Weight 778.72