1620680-19-4
1620680-19-4 structure
- Name: Lp-PLA2-IN-11
- Chemical Name: Lp-PLA2-IN-11
- CAS Number: 1620680-19-4
- Molecular Formula: C22H20F4N4O3
- Molecular Weight: 464.41
- Catalog: Signaling Pathways Metabolic Enzyme/Protease Phospholipase
- Create Date: 2022-04-17 14:55:06
- Modify Date: 2025-08-22 20:51:59
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Lp-PLA2-IN-11 is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). Lp-PLA2 previously known as platelet- activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme involved in hydrolysis of lipoprotein lipids or phospholipids. Lp-PLA2-IN-11 has the potential for the research of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease (extracted from patent WO2014114249A1, compound E145)[1].
| Name | Lp-PLA2-IN-11 |
|---|
| Description | Lp-PLA2-IN-11 is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). Lp-PLA2 previously known as platelet- activating factor acetylhydrolase (PAF-AH), is a phospholipase A2 enzyme involved in hydrolysis of lipoprotein lipids or phospholipids. Lp-PLA2-IN-11 has the potential for the research of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease (extracted from patent WO2014114249A1, compound E145)[1]. |
|---|---|
| Related Catalog | |
| Target |
Lp-PLA2[1] |
| References |
[1]. Zehong Wan, et al. Bicyclic pyrimidone compounds as inhibitors of lp-pla2. Patent WO2014114249A1. |
| Molecular Formula | C22H20F4N4O3 |
|---|---|
| Molecular Weight | 464.41 |