2007955-25-9
2007955-25-9 structure
- Name: IRAP-IN-1
- Chemical Name: IRAP-IN-1
- CAS Number: 2007955-25-9
- Molecular Formula: C35H40N3O4P
- Molecular Weight: 597.696
- Create Date: 2022-07-15 19:37:42
- Modify Date: 2025-08-26 17:28:39
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IRAP-IN-1 is a selective insulin-regulated aminopeptidase (IRAP) inhibitor with IC50 of 32 nM, >25-fold selectivity over ERAP1 and ERAP2.IRAP-IN-1 reduces IRAP-dependent but not ERAP1-dependent cross-presentation by dendritic cells with nanomolar efficacy.
| Name | IRAP-IN-1 |
|---|
| Description | IRAP-IN-1 is a selective insulin-regulated aminopeptidase (IRAP) inhibitor with IC50 of 32 nM, >25-fold selectivity over ERAP1 and ERAP2.IRAP-IN-1 reduces IRAP-dependent but not ERAP1-dependent cross-presentation by dendritic cells with nanomolar efficacy. |
|---|---|
| References | 1. Paraskevi Kokkala, et al. J Med Chem. 2016 Oct 13;59(19):9107-9123. |
| Molecular Formula | C35H40N3O4P |
|---|---|
| Molecular Weight | 597.696 |