IRAP-IN-1

Modify Date: 2025-08-26 17:28:39

IRAP-IN-1 Structure
IRAP-IN-1 structure
Common Name IRAP-IN-1
CAS Number 2007955-25-9 Molecular Weight 597.696
Density N/A Boiling Point N/A
Molecular Formula C35H40N3O4P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of IRAP-IN-1


IRAP-IN-1 is a selective insulin-regulated aminopeptidase (IRAP) inhibitor with IC50 of 32 nM, >25-fold selectivity over ERAP1 and ERAP2.IRAP-IN-1 reduces IRAP-dependent but not ERAP1-dependent cross-presentation by dendritic cells with nanomolar efficacy.

 Names

Name IRAP-IN-1

 IRAP-IN-1 Biological Activity

Description IRAP-IN-1 is a selective insulin-regulated aminopeptidase (IRAP) inhibitor with IC50 of 32 nM, >25-fold selectivity over ERAP1 and ERAP2.IRAP-IN-1 reduces IRAP-dependent but not ERAP1-dependent cross-presentation by dendritic cells with nanomolar efficacy.
References 1. Paraskevi Kokkala, et al. J Med Chem. 2016 Oct 13;59(19):9107-9123.

 Chemical & Physical Properties

Molecular Formula C35H40N3O4P
Molecular Weight 597.696
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