2541604-52-6
2541604-52-6 structure
- Name: ZC0101
- Chemical Name: ZC0101
- CAS Number: 2541604-52-6
- Molecular Formula: C17H15N3O2
- Molecular Weight: 293.32
- Catalog: Signaling Pathways Apoptosis Apoptosis
- Create Date: 2022-06-26 11:26:04
- Modify Date: 2024-01-09 19:25:04
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ZC0101 is a potent, orally active IDO1 and TrxR dual inhibitor with IC50 values of 0.084 μM and 7.98 μM, respectively. ZC0101 effectively induces apoptosis and ROS accumulation in cancer cells[1].
| Name | ZC0101 |
|---|
| Description | ZC0101 is a potent, orally active IDO1 and TrxR dual inhibitor with IC50 values of 0.084 μM and 7.98 μM, respectively. ZC0101 effectively induces apoptosis and ROS accumulation in cancer cells[1]. |
|---|---|
| Related Catalog | |
| Target |
IDO1:0.084 μM (IC50) TrxR:7.98 μM (IC50) |
| In Vivo | ZC0101 (60 mg/kg; p.o.; once) effectively suppresses IDO1 activity in vivo[1]. |
| References |
| Molecular Formula | C17H15N3O2 |
|---|---|
| Molecular Weight | 293.32 |