ALK5-IN-31

Modify Date: 2024-04-02 13:50:01

ALK5-IN-31 Structure
ALK5-IN-31 structure
Common Name ALK5-IN-31
CAS Number 2785430-87-5 Molecular Weight 430.48
Density N/A Boiling Point N/A
Molecular Formula C23H23FN8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ALK5-IN-31


ALK5-IN-31 (compound Ex-08) is a selective ALK-5 inhibitor (IC50≤10 nM), inhibits TGF-β-induced SMAD signaling. ALK5-IN-31 has the potential to inhibit growth of tumour in vivo. ALK5-IN-31 can be used in study of proliferative diseases such as cancer, fibrotic diseases, and systemic sclerosis[1].

 Names

Name ALK5-IN-31

 ALK5-IN-31 Biological Activity

Description ALK5-IN-31 (compound Ex-08) is a selective ALK-5 inhibitor (IC50≤10 nM), inhibits TGF-β-induced SMAD signaling. ALK5-IN-31 has the potential to inhibit growth of tumour in vivo. ALK5-IN-31 can be used in study of proliferative diseases such as cancer, fibrotic diseases, and systemic sclerosis[1].
Related Catalog
Target

ALK-5[1].

References

[1]. Bettina FRANZ, et al. Alk-5 inhibitors and uses thereof. Patent WO2022126133A1.

 Chemical & Physical Properties

Molecular Formula C23H23FN8
Molecular Weight 430.48