80724-20-5

80724-20-5 structure

Name: Tetramethylrhodamine-6-isothiocyanate
Chemical Name: 2-[3-(dimethylamino)-6-dimethylazaniumylidenexanthen-9-yl]-4-isothiocyanatobenzoate
CAS Number: 80724-20-5
Molecular Formula: C₂₅H₂₁N₃O₃S
Molecular Weight: 443.51800
Catalog: Research Areas Others
Create Date: 2018-05-22 08:00:00
Modify Date: 2025-08-25 07:40:59
Tetramethylrhodamine-6-isothiocyanate is a potent fluorescent tracer. Tetramethylrhodamine-6-isothiocyanate can be used as an probe for haptenated proteins/peptides for the research of contact allergy. Tetramethylrhodamine-6-isothiocyanate can be used as a tracer for the confocal imaging in living cells[1][2].

Name	2-[3-(dimethylamino)-6-dimethylazaniumylidenexanthen-9-yl]-4-isothiocyanatobenzoate
Synonyms	6-TRITC T3163_SIAL BIT3022 5(6)-Tetramethylrhodamine isothiocyanate Tetramethylrhodamine-6-isothiocyanate Tetramethylrhodamine isothiocyanate

Description	Tetramethylrhodamine-6-isothiocyanate is a potent fluorescent tracer. Tetramethylrhodamine-6-isothiocyanate can be used as an probe for haptenated proteins/peptides for the research of contact allergy. Tetramethylrhodamine-6-isothiocyanate can be used as a tracer for the confocal imaging in living cells[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Tetramethylrhodamine-6-isothiocyanate is relatively photostable and robust toward pH changes[1]. Tetramethylrhodamine-6-isothiocyanate as an extreme sensitizer induces a massive cell proliferation and gave an EC3 value of 0.92 mM (0.040%) in the murine LLNA (local lymph node assay)[1]. Tetramethylrhodamine-6-isothiocyanate (1.0 mg; 2h) can used as fluorescence probe for confocal imaging in Fe3O4@PDA incubated living cells[2].
References	[1]. Karlsson I, et al. Peptide Reactivity of Isothiocyanates--Implications for Skin Allergy. Sci Rep. 2016 Feb 17;6:21203. [2]. Yue Q ,et al . A versatile ethanol-mediated polymerization of dopamine for efficient surface modification and the construction of functional core-shell nanostructures. J Mater Chem B. 2013 Nov 28;1(44):6085-6093.

Hazard Codes	Xn: Harmful;