Tetramethylrhodamine-6-isothiocyanate

Modify Date: 2025-08-25 07:40:59

Tetramethylrhodamine-6-isothiocyanate Structure
Tetramethylrhodamine-6-isothiocyanate structure
Common Name Tetramethylrhodamine-6-isothiocyanate
CAS Number 80724-20-5 Molecular Weight 443.51800
Density N/A Boiling Point N/A
Molecular Formula C25H21N3O3S Melting Point N/A
MSDS Chinese USA Flash Point N/A

 Use of Tetramethylrhodamine-6-isothiocyanate


Tetramethylrhodamine-6-isothiocyanate is a potent fluorescent tracer. Tetramethylrhodamine-6-isothiocyanate can be used as an probe for haptenated proteins/peptides for the research of contact allergy. Tetramethylrhodamine-6-isothiocyanate can be used as a tracer for the confocal imaging in living cells[1][2].

 Names

Name 2-[3-(dimethylamino)-6-dimethylazaniumylidenexanthen-9-yl]-4-isothiocyanatobenzoate
Synonym More Synonyms

 Tetramethylrhodamine-6-isothiocyanate Biological Activity

Description Tetramethylrhodamine-6-isothiocyanate is a potent fluorescent tracer. Tetramethylrhodamine-6-isothiocyanate can be used as an probe for haptenated proteins/peptides for the research of contact allergy. Tetramethylrhodamine-6-isothiocyanate can be used as a tracer for the confocal imaging in living cells[1][2].
Related Catalog
In Vitro Tetramethylrhodamine-6-isothiocyanate is relatively photostable and robust toward pH changes[1]. Tetramethylrhodamine-6-isothiocyanate as an extreme sensitizer induces a massive cell proliferation and gave an EC3 value of 0.92 mM (0.040%) in the murine LLNA (local lymph node assay)[1]. Tetramethylrhodamine-6-isothiocyanate (1.0 mg; 2h) can used as fluorescence probe for confocal imaging in Fe3O4@PDA incubated living cells[2].
References

[1]. Karlsson I, et al. Peptide Reactivity of Isothiocyanates--Implications for Skin Allergy. Sci Rep. 2016 Feb 17;6:21203.

[2]. Yue Q ,et al . A versatile ethanol-mediated polymerization of dopamine for efficient surface modification and the construction of functional core-shell nanostructures. J Mater Chem B. 2013 Nov 28;1(44):6085-6093.

 Chemical & Physical Properties

Molecular Formula C25H21N3O3S
Molecular Weight 443.51800
Exact Mass 443.13000
PSA 104.20000
LogP 4.76390
Storage condition 2~8°C

 Safety Information

Hazard Codes Xn: Harmful;

 Synonyms

6-TRITC
T3163_SIAL
BIT3022
5(6)-Tetramethylrhodamine isothiocyanate
Tetramethylrhodamine-6-isothiocyanate
Tetramethylrhodamine isothiocyanate
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