911004-72-3

911004-72-3 structure
911004-72-3 structure
  • Name: Furowanin A
  • Chemical Name: Furowanin A
  • CAS Number: 911004-72-3
  • Molecular Formula: C25H26O7
  • Molecular Weight: 438.47
  • Catalog: Natural product Flavonoids
  • Create Date: 2018-06-19 20:05:50
  • Modify Date: 2025-08-28 11:17:14
  • Furowanin A is a flavonoid with anti-neoplastic effects. Furowanin A inhibits STAT3/Mcl-1 axis to suppress proliferation, block cell cycle progression, induce apoptosis and promote autophagy. Furowanin A potently inhibits colorectal cancer (CRC) cells[1].

Name Furowanin A
Synonyms 6-(3,4-Dihydroxyphenyl)-4-hydroxy-2-(2-hydroxy-2-propanyl)-9-(3-methyl-2-buten-1-yl)-2,3-dihydro-5H-furo[3,2-g]chromen-5-one
5H-Furo[3,2-g][1]benzopyran-5-one, 6-(3,4-dihydroxyphenyl)-2,3-dihydro-4-hydroxy-2-(1-hydroxy-1-methylethyl)-9-(3-methyl-2-buten-1-yl)-
Description Furowanin A is a flavonoid with anti-neoplastic effects. Furowanin A inhibits STAT3/Mcl-1 axis to suppress proliferation, block cell cycle progression, induce apoptosis and promote autophagy. Furowanin A potently inhibits colorectal cancer (CRC) cells[1].
Related Catalog
Target

Mcl-1

STAT3

References

[1]. Ma Z, et al. Furowanin A-induced autophagy alleviates apoptosis and promotes cell cycle arrest via inactivation STAT3/Mcl-1 axis in colorectal cancer. Life Sci. 2019 Feb 1;218:47-57.  

Density 1.4±0.1 g/cm3
Boiling Point 697.7±55.0 °C at 760 mmHg
Molecular Formula C25H26O7
Molecular Weight 438.47
Flash Point 240.3±25.0 °C
Exact Mass 438.167847
PSA 120.36000
LogP 5.34
Vapour Pressure 0.0±2.3 mmHg at 25°C
Index of Refraction 1.661
Hazard Codes Xi
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