603-45-2

603-45-2 structure

Name: Aurin
Chemical Name: 4-[bis(4-hydroxyphenyl)methylidene]cyclohexa-2,5-dien-1-one
CAS Number: 603-45-2
Molecular Formula: C₁₉H₁₄O₃
Molecular Weight: 290.31
Catalog: Biochemical Biochemical reagent Acid-base indicator
Create Date: 2018-06-18 01:28:21
Modify Date: 2024-01-11 19:53:40
Rosolic Acid is an activator of Nrf2, as well as its downstream targets. Rosolic Acid increases the levels of angiogenic factors, decreases inflammation (TNF-α and IL-1β) and apoptotic markers (CXCL10 and CCL2). Rosolic Acid restores the function of pancreatic cells and protects endothelial cells (ECs) from endoplasmic reticulum stressed[1].

Name	4-[bis(4-hydroxyphenyl)methylidene]cyclohexa-2,5-dien-1-one
Synonyms	4-(p,p'-Dihydroxybenzhydrylidene)-2,5-cyclohexadien-1-one Aurin No. 555 MFCD00001624 2,5-Cyclohexadien-1-one, 4-[bis(4-hydroxyphenyl)methylene]- EINECS 210-041-8 4-[bis(4-hydroxyphenyl)methylene]cyclohexa-2,5-dien-1-one Aurin 4-<bis(4-hydroxyphenyl)methylene>-2,5-cyclohexadienone 2,5-Cyclohexadien-1-one, 4-(bis(4-hydroxyphenyl)methylene)- rosolic acid 4-[Bis(4-hydroxyphenyl)methylene]-2,5-cyclohexadien-1-one Corallin Spirit Soluble 4,4'-Dihydroxyfuchsone 4-(Bis(p-hydroxyphenyl)methylene)cyclohexa-2,5-dien-1-one 4-[bis(4-hydroxyphenyl)methylidene]cyclohexa-2,5-dien-1-one Aurine Corallin p-Rosolic acid Spirit Aurine 4-[bis-(4-hydroxyphenyl)methylene]-cyclohexa-2,5-dienone Rosalic Acid CI 43800 Pararosolic Acid

Description	Rosolic Acid is an activator of Nrf2, as well as its downstream targets. Rosolic Acid increases the levels of angiogenic factors, decreases inflammation (TNF-α and IL-1β) and apoptotic markers (CXCL10 and CCL2). Rosolic Acid restores the function of pancreatic cells and protects endothelial cells (ECs) from endoplasmic reticulum stressed[1].
Related Catalog	Signaling Pathways >> NF-κB >> Keap1-Nrf2 Research Areas >> Metabolic Disease
References	[1]. Amin KN, et al. Effect of Rosolic acid on endothelial dysfunction under ER stress in pancreatic microenvironment. Free Radic Res. 2021 Jun;55(6):698-713.

Density	1.3±0.1 g/cm3
Boiling Point	543.0±50.0 °C at 760 mmHg
Melting Point	ca. 308ºC (decomposes)
Molecular Formula	C₁₉H₁₄O₃
Molecular Weight	290.31
Flash Point	296.2±26.6 °C
Exact Mass	290.094299
PSA	57.53000
LogP	3.15
Vapour Pressure	0.0±1.5 mmHg at 25°C
Index of Refraction	1.691
Storage condition	Store at room temperature.
Water Solubility	Solubility Practically insoluble in water, benzene; freely soluble in ethanol

Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2914501900

HS Code	2914501900
Summary	2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

603-45-2	5664-34-6
569-58-4	63451-31-0