Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Cynarin
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

BioBioPha
China
Product Name: 1,4-Di-O-caffeoylquinic acid
Price: ￥Inquiry/5mg
Purity: 98.0%
Stocking Period: 10 Day
Contact: Xueping-Zheng

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Cynarin
Price: ￥988.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Cynarin
Price: $280.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

1182-34-9

1182-34-9 structure

1182-34-9 structure

Name: Cynarin
Chemical Name: cynarin
CAS Number: 1182-34-9
Molecular Formula: C₂₅H₂₄O₁₂
Molecular Weight: 516.45
Catalog: Biochemical Plant extracts
Create Date: 2018-07-21 17:29:13
Modify Date: 2024-01-04 02:46:16
1,4-Dicaffeoylquinic acid (1,4-DCQA) is a phenylpropanoid from Xanthii fructus, inhibits LPS-stimulated TNF-α production[1].

Name	cynarin
Synonyms	1,3-DICAFFEOYLQUINIC ACID 1.3-O-Dicaffeoylquinic acid Indena Cinaran cin plemocil (1S,2S,3S,4R)-1,4-bis{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}-2,3-dihydroxycyclohexanecarboxylic acid cinarcaf Cyclohexanecarboxylic acid, 1,4-bis[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-2,3-dihydroxy-, (1S,2S,3S,4R)- CINARINE cynarine (1S,2S,3S,4R)-1,4-Bis{[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoyl]oxy}-2,3-dihydroxycyclohexanecarboxylic acid cyclohexanecarboxylic acid, 1,4-bis[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-2,3-dihydroxy-, (1S,2S,3S,4R)- listrocol cyn CINARAN EINECS 214-655-7 (1S,2S,3S,4R)-1,2,3-trihydroxycyclohexane-1,4-diyl (2E,2'E)bis[3-(3,4-dihydroxyphenyl)acrylate]

Description	1,4-Dicaffeoylquinic acid (1,4-DCQA) is a phenylpropanoid from Xanthii fructus, inhibits LPS-stimulated TNF-α production[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Yoo SR, et al. Phytochemical Analysis on Quantification and the Inhibitory Effects on Inflammatory Responses from the Fruit of Xanthii fructus. Pharmacogn Mag. 2015 Oct;11(Suppl 4):S585-91.

Density	1.6±0.1 g/cm3
Boiling Point	819.9±65.0 °C at 760 mmHg
Melting Point	225-227ºC
Molecular Formula	C₂₅H₂₄O₁₂
Molecular Weight	516.45
Flash Point	278.1±27.8 °C
Exact Mass	516.126770
PSA	211.28000
LogP	1.99
Vapour Pressure	0.0±3.1 mmHg at 25°C
Index of Refraction	1.719

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GD8970000

CHEMICAL NAME :: Cinnamic acid, 3,4-dihydroxy-, 1-carboxy-3,5-dihydroxy-1,4-cyclohexylene ester, hydrate

CAS REGISTRY NUMBER :: 1182-34-9

LAST UPDATED :: 199406

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C25-H24-O12.H2-O

MOLECULAR WEIGHT :: 534.51

WISWESSER LINE NOTATION :: L6TJ AQ BOV1U1R CQ DQ& CQ EVQ EOV1U1R CQ DQ &QH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 117,63,1958

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1900 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 117,63,1958

Hazard Codes	Xn;N
Risk Phrases	R22;R43;R50/53
Safety Phrases	S36/37-S60-S61
RIDADR	UN 3077
HS Code	2932999099

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%