943858-70-6

943858-70-6 structure
943858-70-6 structure
  • Name: N3-C3-NHS ester
  • Chemical Name: Butanoic acid, 4-azido-, 2,5-dioxo-1-pyrrolidinyl ester
  • CAS Number: 943858-70-6
  • Molecular Formula: C8H10N4O4
  • Molecular Weight: 226.18900
  • Catalog: Research Areas Cancer
  • Create Date: 2016-10-03 01:43:11
  • Modify Date: 2024-01-02 00:04:55
  • N3-C3-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Name Butanoic acid, 4-azido-, 2,5-dioxo-1-pyrrolidinyl ester
Synonyms 4-azidobutyrate-n-hydroxysuccinimide ester
Description N3-C3-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Related Catalog
Target

Noncleavable

References

[1]. Pyrrolobenzodiazepine Dimer Antibody-Drug Conjugates: Synthesis and Evaluation of Noncleavable Drug-Linkers. J Med Chem. 2017 Dec 14;60(23):9490-9507.

Molecular Formula C8H10N4O4
Molecular Weight 226.18900
Exact Mass 226.07000
PSA 113.43000
LogP 0.07476
HS Code 2929909090
HS Code 2929909090
Summary 2929909090 other compounds with other nitrogen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%