13739-02-1
13739-02-1 structure
- Name: Diacerein
- Chemical Name: 1,8-Diacetoxy-3-carboxyanthraquinone
- CAS Number: 13739-02-1
- Molecular Formula: C19H12O8
- Molecular Weight: 368.294
- Catalog: API Immune function drug Immunosuppressive drug
- Create Date: 2018-05-12 08:00:00
- Modify Date: 2026-07-01 00:41:17
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Diacerein, a interleukin-1 beta inhibitor, is a slow-acting medicine of the class anthraquinone used to treat joint diseases.Target: IL-1 betaDiacerein, a interleukin-1 beta inhibitor, is a slow-acting medicine of the class anthraquinone used to treat joint diseases. Diacerein works by blocking the actions of interleukin-1 beta, a protein involved in the inflammation and destruction of cartilage that play a role in the development of symptoms of degenerative joint diseases such as osteoarthritis. Due to its specific mode of action, which does not involve the inhibition of prostaglandin synthesis, diacerein has been shown to have anti-osteoarthritis and cartilage stimulating properties in vitro and animal models, together with analgesic and anti-inflammatory properties. Due to its excellent gastro-intestinal tolerance, a combination therapy with an analgesic or a NSAID may be recommended during the first 2-4 weeks of treatment. From Wikipedia.
| Name | 1,8-Diacetoxy-3-carboxyanthraquinone |
|---|---|
| Synonyms |
MFCD00468030
Fisiodar 4,5-diacetoxy-9,10-diketo-anthracene-2-cboxylic acid Diacerein, 10 mM in DMSO EINECS 237-310-2 Diacerein> Diacerein //BP 4,5-diacetyhein 4,5-diacetyloxy-9,10-dioxo-2-anthracenecboxylic acid Diacerein for thritis Treatment 4,5-diacetyloxy-9,10-dioxo-anthracene-2-cboxylic acid DIACETYL RHEIN(P) Diacerein (1,8-Diacetoxy-3-cboxyanthraquinone) 4,5-Diacetoxy-9,10-dihydro-9,10-dioxo-2-anthracenecboxylic acid Diacerein(Y0001595) Diacerein, （HPLC) 1,8-DIACETOXY-3-CBOXYANTHRAQUINONE Rhein Diacetate Diacerein API 9,10-dihydro-4,5-diacetoxy-9,-anthracenecboxylicacid 4,5-Bis(acetyloxy)-9,10-dihydro-9,10-dioxo-2-anthracenecboxylic Acid Diacerein (Diacerhein) 4,5-Diacetoxyanthraquinone-2-carboxylic Acid 1,8-diacetoxyanthraquinone-3-cboxylicacid diacetylrhein ICN-17261 4,5-Diacetoxy-9,10-dioxo-2-anthracenecboxylic acid 4,5-diacetoxy-9,10-dioxo-9,10-dihydroanthracene-2-cboxylic acid 4,5-diacetylrhein DIACEREIN Diacerein IP ICN17261 4,5-diacetoxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid SF 277 Diacerein - Bio-X Diacetine 9,10-dihydro-4,5-dihydroxy-9,10-dioxo-2-anthroicacidiacetate 4,5-diacetyloxy-9,10-dioxoanthracene-2-cboxylic acid 4,5-Diacetoxyanthraquinone-2-cboxylic Acid 4,5-Diacetoxy-9,10-dioxo-9,10-dihydro-2-anthracenecarboxylic acid DIACERHEIN DIACETYL RHEIN Diacerein CRS trod DIACERHEIN;DIACETYHEIN;FISIOD;TROD 4,5-bis(acetyloxy)-9,10-dihydro-9,10-dioxo-2-anthracenecboxylicaci 4,5-Bis(acetyloxy)-9,10-dioxo-2-anthracenecboxylic acid Diacerhein|||Fisiod|||Diacetyhein 2-Anthracenecboxylic acid, 4,5-bis(acetyloxy)-9,10-dihydro-9,10-dioxo Diacerein impurity mixture CRS rhein,diacetate 4,5-Bis(acetyloxy)-9,10-dihydro-9,10-dioxo-2-anthracenecarboxylic Acid artrodar Diacereine DiacereinQ: What is Diacerein Q: What is the CAS Number of Diacerein Q: What is the storage condition of Diacerein Q: What e the applications of Diacerein DAR 9,10-dihydro-4,5-dihydroxy-9,10-dioxo-2-anthroicaciddiacetate Fisiod Diacerein 13-1 |
| Description | Diacerein, a interleukin-1 beta inhibitor, is a slow-acting medicine of the class anthraquinone used to treat joint diseases.Target: IL-1 betaDiacerein, a interleukin-1 beta inhibitor, is a slow-acting medicine of the class anthraquinone used to treat joint diseases. Diacerein works by blocking the actions of interleukin-1 beta, a protein involved in the inflammation and destruction of cartilage that play a role in the development of symptoms of degenerative joint diseases such as osteoarthritis. Due to its specific mode of action, which does not involve the inhibition of prostaglandin synthesis, diacerein has been shown to have anti-osteoarthritis and cartilage stimulating properties in vitro and animal models, together with analgesic and anti-inflammatory properties. Due to its excellent gastro-intestinal tolerance, a combination therapy with an analgesic or a NSAID may be recommended during the first 2-4 weeks of treatment. From Wikipedia. |
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| Related Catalog | |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 631.5±55.0 °C at 760 mmHg |
| Melting Point | 217-2180C |
| Molecular Formula | C19H12O8 |
| Molecular Weight | 368.294 |
| Flash Point | 231.8±25.0 °C |
| Exact Mass | 368.053223 |
| PSA | 124.04000 |
| LogP | 1.99 |
| Vapour Pressure | 0.0±1.9 mmHg at 25°C |
| Index of Refraction | 1.634 |
| Storage condition | Refrigerator |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Phrases | 36/37/38 |
| Safety Phrases | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | CB8781000 |
| HS Code | 2918990090 |
| Precursor 8 | |
|---|---|
| DownStream 2 | |
| HS Code | 2918990090 |
|---|---|
| Summary | 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |