57-71-6

57-71-6 structure

Name: Diacetyl monoxime
Chemical Name: Diacetylmonoxime
CAS Number: 57-71-6
Molecular Formula: C₄H₇NO₂
Molecular Weight: 101.104
Catalog: Chemical reagent Organic reagent 肟
Create Date: 2018-04-17 08:00:00
Modify Date: 2026-07-02 10:47:55
Biacetyl monoxime (Diacetyl monoxime), a myosin ATPase inhibitor, is a skeletal and cardiac muscle contraction inhibitor. Biacetyl monoxime induces sarcoplasmic reticulum Ca2+ release[1][2].

Name	Diacetylmonoxime
Synonyms	BIACETYL MONOXIME 2,3-Butanedione monoxime,BDM, Biacetyl monoxime, Diacetyl monoxime Diacetylmonoxime, ade DiacetylMonoxime diacetylmonoximecas DIACETYLMONOXIME extrapure 2,3-Butanedione 2-Monoxime - - Calbiochem Diacetyl monoxime (2,3-Butanedione monoxime) ISONITROSOETHYL METHYL KETONE 2,3-BUTANEDIONE 2-MONOXIME Biacethylmonoxime 2,3-BUTANEDIONE OXIME Diacetyl Monoxime > 2-oxime2,3-butanedione Diacetyl Monoxime 〔2,3-Butanedione-2-oxime〕 (3E)-3-hydroxyimino-2-butanone 2-Hydroxyimino-3-butanone 2,3-Butanedione,2-oxime EINECS 200-348-5 2,3-BUTANEDIONE-2-OXIME Methyliso-nitroethylketone 2,3-BUTANEDIONE, MONO-OXIME (E)-3-(hydroxyiMino)butan-2-one MFCD00002116 3-Butanedione monooxime 2-Oximino-3-Butanone Biacetyl Monoxime 2,3-Butanedione 2-Oxime Isonitrosoethyl Methyl Ketone Diacetyl monoxime p.a BIACETYL MONOOXIME DiacetylmonoximeSolutionA.R Diacety1monoxime 2,3-Butanedione monoxime iso-Nitroethylmethylketone (3E)-3-(Hydroxyimino)-2-butanone Diacetyl Monoxime (Powder/), Fisher Chemical DIACETYL MONOOXIME DIACETYL MONOXIME 3-Oximino-2-butanone 3-Hydroxyimino-2-butanone BDM, Biacetyl monoxime, Diacetyl monoxime iso-Nitromethylethylketone 2,3-BUTANEDIONE MONOXIME (3E)-3-hydroxyiminobutan-2-one (2E)-butane-2,3-dione oxime ButanedioneMonoxime 2,3-BUTANEDIONE 2-OXIME 3-(Hydroxyimino)butan-2-one 2,3-Butanedione 3-monoxime Diacetyl monoxime M (3E)-3-(Hydroxyimino)butan-2-one (2E)-2,3-Butanedione 2-oxime

Description	Biacetyl monoxime (Diacetyl monoxime), a myosin ATPase inhibitor, is a skeletal and cardiac muscle contraction inhibitor. Biacetyl monoxime induces sarcoplasmic reticulum Ca2+ release[1][2].
Related Catalog	Research Areas >> Metabolic Disease
References	[1]. Kohsuke Hashimoto, et al. The myosin ATPase inhibitor, 2,3-butanedione 2-monoxime, prevents protein secretion by the basidiomycete Coprinopsis cinerea. Biotechnol Lett. 2011 Apr;33(4):769-75. [2]. R M Phillips, et al. 2,3-Butanedione 2-monoxime (BDM) induces calcium release from canine cardiac sarcoplasmic reticulum. Biochem Biophys Res Commun. 1996 Dec 4;229(1):154-7.

Density	1.1±0.1 g/cm3
Boiling Point	185.5±9.0 °C at 760 mmHg
Melting Point	75-78 °C(lit.)
Molecular Formula	C₄H₇NO₂
Molecular Weight	101.104
Flash Point	66.0±18.7 °C
Exact Mass	101.047676
PSA	49.66000
LogP	-0.47
Vapour Pressure	0.3±0.7 mmHg at 25°C
Index of Refraction	1.452
Stability	Stable. Incompatible with strong oxidizing agents.
Water Solubility	5 g/100 mL (20 ºC)

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 53,1143,1964 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TOXIC EFFECTS :: Gastrointestinal - hypermotility, diarrhea Gastrointestinal - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 119,522,1957 *** REVIEWS *** TOXICOLOGY REVIEW JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 53,1143,1964 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M0440 No. of Facilities: 718 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 4820 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M0440 No. of Facilities: 370 (estimated) No. of Industries: 2 No. of Occupations: 5 No. of Employees: 1974 (estimated) No. of Female Employees: 1730 (estimated)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xn:Harmful
Risk Phrases	R20/21/22;R36/37/38
Safety Phrases	S22-S24/25-S36/37/39-S26
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	EK3150000
HS Code	29280090

HS Code	2928000090
Summary	2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%