Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Urocanic acid
Price: ￥818.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Liu jia

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Urocanic acid
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

104-98-3

104-98-3 structure

104-98-3 structure

Name: Urocanic acid
Chemical Name: urocanic acid
CAS Number: 104-98-3
Molecular Formula: C₆H₆N₂O₂
Molecular Weight: 138.124
Catalog: Research Areas Others
Create Date: 2018-09-11 11:33:26
Modify Date: 2024-01-04 15:21:24
Urocanic acid, produced in the upper layers of mammalian skin, is a major absorber of ultraviolet radiation (UVR).

Name	urocanic acid
Synonyms	(2E)-3-(1H-Imidazol-4-yl)acrylic acid urocanoic acid (2E)-3-(1H-imidazol-4-yl)prop-2-enoic acid (E)-3-(1H-imidazol-4-yl)acrylic acid RARECHEM AL BK 0762 (Z/E)-3-(1H-imidazol-4-yl)-2-propenoic acid 3-(1H-imidazol-4-yl)prop-2-enoic acid imidazoleacrylicacid (E)-3-(1H-imidazol-4-yl)-2-propenoic acid 3-imidazol-4-ylacrylic Urocanate 4-Imidazoleacrylic Acid 2-Propenoic acid, 3-(1H-imidazol-4-yl)-, (2E)- UROCANINIC ACID Trans-Urocanic acid (E)-3-(1H-Imidazol-5-yl)-2-propenoic acid 3-(1H-Imidazol-4-yl)acrylic acid Urocanic caid Urocanic acid 3-imidazol-4-yl-acrylic acid 2-propenoic acid, 3-(1H-imidazol-5-yl)-, (2E)- urosanic acid 4-imidazoleacrylate MFCD00005203 (2E)-3-(1H-Imidazol-5-yl)acrylic acid EINECS 203-258-4

Description	Urocanic acid, produced in the upper layers of mammalian skin, is a major absorber of ultraviolet radiation (UVR).
Related Catalog	Natural Products >> Acids and Aldehydes Research Areas >> Others
Target	Human Endogenous Metabolite
In Vitro	Urocanic acid (UCA) is formed in the upper layers of the epidermis where filaggrin, a histidine-rich filamentous protein produced after caspase-14 cleavage of profilaggrin, is broken down by proteinases into component amino acids[1].
References	[1]. Gibbs NK, et al. Recent advances in urocanic acid photochemistry, photobiology and photoimmunology. Photochem Photobiol Sci. 2008 Jun;7(6):655-67.

Density	1.4±0.1 g/cm3
Boiling Point	456.9±20.0 °C at 760 mmHg
Melting Point	226-228 °C(lit.)
Molecular Formula	C₆H₆N₂O₂
Molecular Weight	138.124
Flash Point	230.1±21.8 °C
Exact Mass	138.042923
PSA	65.98000
LogP	0.01
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.674
Storage condition	2-8°C
Water Solubility	SLIGHTLY SOLUBLE

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NI3425200

CHEMICAL NAME :: Imidazole-4-acrylic acid

CAS REGISTRY NUMBER :: 104-98-3

BEILSTEIN REFERENCE NO. :: 0081405

LAST UPDATED :: 199701

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C6-H6-N2-O2

MOLECULAR WEIGHT :: 138.14

WISWESSER LINE NOTATION :: T5M CNJ D1U1VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: DNA inhibition

TEST SYSTEM :: Human Cells - not otherwise specified

DOSE/DURATION :: 1 mmol/L

REFERENCE :: JIDEAE Journal of Investigative Dermatology. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1938- Volume(issue)/page/year: 65,400,1975

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	NI3425200
HS Code	29332990

71-00-1 structure

71-00-1

~%

104-98-3 structure

104-98-3

Literature: Analytical Chemistry, , vol. 77, # 4 p. 1013 - 1019

Precursor 1
71-00-1
DownStream 4
31434-93-2 102676-60-8 49549-75-9 56662-92-1

HS Code	29332990