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352439-36-2

352439-36-2 structure
352439-36-2 structure
  • Name: Azide-PEG8-alcohol
  • Chemical Name: 2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
  • CAS Number: 352439-36-2
  • Molecular Formula: C16H33N3O8
  • Molecular Weight: 395.44900
  • Catalog: Chemical reagent Organic reagent Azide
  • Create Date: 2016-10-04 02:00:11
  • Modify Date: 2024-01-09 15:38:27
  • Azide-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
Synonyms 1-azido-23-hydroxy-3,6,9,12,15,18,21-heptaoxatricosane
AmbotzPEG1088
Azido-PEG (n=7)
23-azido-3,6,9,12,15,18,21-heptaoxatricosan-1-ol
O-(2-azidoethyl)heptaethyleneglycol
3,6,9,12,15,18,21-Heptaoxatricosan-1-ol,23-azido
Description Azide-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C16H33N3O8
Molecular Weight 395.44900
Exact Mass 395.22700
PSA 134.59000
Storage condition 2-8°C
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi
Risk Phrases 36/37/38
Safety Phrases 26
RIDADR NONH for all modes of transport
HS Code 2929909090
HS Code 2929909090
Summary 2929909090 other compounds with other nitrogen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%