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118266-99-2

118266-99-2 structure
118266-99-2 structure
  • Name: crotmadine
  • Chemical Name: Isodorsmanin A
  • CAS Number: 118266-99-2
  • Molecular Formula: C20H20O4
  • Molecular Weight: 324.37
  • Catalog: Natural product Chalcone
  • Create Date: 2016-11-04 21:45:46
  • Modify Date: 2024-03-11 10:15:59
  • Isodorsmanin A is an anti-inflammatory agent. Isodorsmanin A suppresses the production of inflammatory mediators and proinflammatory cytokines. Isodorsmanin A inhibits the phosphorylation of JNK, MAPK[1].

Name Isodorsmanin A
Synonyms (2E)-1-(5-hydroxy-2,2-dimethyl-3,4-dihydro-2H-chromen-8-yl)-3-(4-hydroxyphenyl)prop-2-en-1-one
2-Propen-1-one, 1-(3,4-dihydro-5-hydroxy-2,2-dimethyl-2H-1-benzopyran-8-yl)-3-(4-hydroxyphenyl)-, (2E)-
(2E)-1-(5-Hydroxy-2,2-dimethyl-3,4-dihydro-2H-chromen-8-yl)-3-(4-hydroxyphenyl)-2-propen-1-one
crotmadine
Description Isodorsmanin A is an anti-inflammatory agent. Isodorsmanin A suppresses the production of inflammatory mediators and proinflammatory cytokines. Isodorsmanin A inhibits the phosphorylation of JNK, MAPK[1].
Related Catalog
References

[1]. Chung YC, et al. Isodorsmanin A Prevents Inflammatory Response in LPS-Stimulated Macrophages by Inhibiting the JNK and NF-κB Signaling Pathways. Curr Issues Mol Biol. 2023 Feb 13;45(2):1601-1612.  

Density 1.2±0.1 g/cm3
Boiling Point 549.9±50.0 °C at 760 mmHg
Melting Point 239-240℃
Molecular Formula C20H20O4
Molecular Weight 324.37
Flash Point 198.7±23.6 °C
Exact Mass 324.136169
PSA 66.76000
LogP 4.75
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.633
Hazard Codes Xi
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