114567-34-9

114567-34-9 structure

Name: Boeravinone B
Chemical Name: Boeravinone B
CAS Number: 114567-34-9
Molecular Formula: C₁₇H₁₂O₆
Molecular Weight: 312.274
Catalog: Natural product Flavonoids
Create Date: 2017-06-01 01:14:54
Modify Date: 2024-01-03 00:28:21
Boeravinone B, a dual inhibitor of NorA bacterial efflux pump of Staphylococcus aureus and human P-Glycoprotein, reduces the biofilm formation and intracellular invasion of bacteria. Boeravinone B act as anti-aging and anti-apoptosis phyto-molecules during oxidative stress[1][2].

Name	Boeravinone B
Synonyms	6,9,11-Trihydroxy-10-methyl-[1]benzopyrano[3,4-b][1]benzopyran-12(6H)-one [1]Benzopyrano[3,4-b][1]benzopyran-12(6H)-one, 6,9,11-trihydroxy-10-methyl- 6,9,11-Trihydroxy-10-methylchromeno[3,4-b]chromen-12(6H)-one

Description	Boeravinone B, a dual inhibitor of NorA bacterial efflux pump of Staphylococcus aureus and human P-Glycoprotein, reduces the biofilm formation and intracellular invasion of bacteria. Boeravinone B act as anti-aging and anti-apoptosis phyto-molecules during oxidative stress[1][2].
Related Catalog	Research Areas >> Infection Research Areas >> Inflammation/Immunology Signaling Pathways >> Membrane Transporter/Ion Channel >> P-glycoprotein
In Vitro	Boeravinone B is also active against a methicillin-resistant S. aureus (MRSA) strain, which showed a fourfold reduction in the ciprofloxacin MIC[1].
References	[1]. Samsher Singh, Boeravinone B, A Novel Dual Inhibitor of NorA Bacterial Efflux Pump of Staphylococcus aureus and Human P-Glycoprotein, Reduces the Biofilm Formation and Intracellular Invasion of Bacteria. Front Microbiol. 2017 Oct 4;8:1868. [2]. Shivtej P Biradar, et al. Chebulinic acid and Boeravinone B act as anti-aging and anti-apoptosis phyto-molecules during oxidative stress. Mitochondrion. 2019 May;46:236-246.

Hazard Codes	N
RIDADR	NONH for all modes of transport