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87239-81-4

87239-81-4 structure
87239-81-4 structure
  • Name: Cefpodoxime Proxetil
  • Chemical Name: cefpodoxime proxetil
  • CAS Number: 87239-81-4
  • Molecular Formula: C21H27N5O9S2
  • Molecular Weight: 557.597
  • Catalog: API Antibiotics Cephalosporin
  • Create Date: 2018-03-02 08:00:00
  • Modify Date: 2024-01-04 19:45:00
  • Cefpodoxime Proxetil is a first oral and broad spectrum antibiotic that belongs to the third generation of cephalosporin. Cefpodoxime Proxetil binds to penicillin binding proteins (PBPs), which inhibits peptidoglycan synthesis, finally results in interfering bacterial cell wall biosynthesis[1].

Name cefpodoxime proxetil
Synonyms R-3763
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-(methoxymethyl)-8-oxo-, 1-[[(1-methylethoxy)carbonyl]oxy]ethyl ester, (6R,7R)-
Cefodox
JP,USP
Cefpodoxime proxetil
1-isopropoxycarbonyloxyethyl (6R,7R)-7-[2-(2-aminothiazol-4-yl)-2-(Z)-(methoxyimino)acetamido]-3-(methoxymethyl)-3-cephem-4-carboxylate
Orelox
CS-807
1-({[(1-methylethyl)oxy]carbonyl}oxy)ethyl (6R,7R)-7-({(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(methyloxy)imino]acetyl}amino)-3-[(methyloxy)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Cefpodoxime 1-(Isopropoxycarbonyloxy)ethyl ester
Podomexef
BANAN
UNII:2TB00A1Z7N
[6R-[6a,7b(Z)]]-7-[[(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid 1-[[(1-Methylethoxy)carbonyl]oxy]ethyl Ester
MFCD00864906
1-[(Isopropoxycarbonyl)oxy]ethyl (6R,7R)-7-{[(2-amino-1,3-thiazol-4-yl)(methoxyimino)acetyl]amino}-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
1-(Isopropoxycarbonyloxy)ethyl (6R,7R)-7-[2-(2-Amino-4-thiazolyl)-(Z)-2-(methoxyimino)acetamido]-3-methoxymethyl-3-cephem-4-carboxylate
1-[(Isopropoxycarbonyl)oxy]ethyl (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
cefpodoxime 1-(isopropyloxycarbonyloxy)ethyl ester
cefprodoxime proxetil
1-{[(1-Methylethoxy)carbonyl]oxy}ethyl-(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-2-carboxylat
Otreon
cefpodoxime-proxetil
1-{[(1-methylethoxy)carbonyl]oxy}ethyl (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)-1-oxoethyl]amino]-3-(methoxymethyl)-8-oxo-, 1-[[(1-methylethoxy)carbonyl]oxy]ethyl ester, (6R,7R)-
1-{[(propan-2-yloxy)carbonyl]oxy}ethyl (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Vantin
Description Cefpodoxime Proxetil is a first oral and broad spectrum antibiotic that belongs to the third generation of cephalosporin. Cefpodoxime Proxetil binds to penicillin binding proteins (PBPs), which inhibits peptidoglycan synthesis, finally results in interfering bacterial cell wall biosynthesis[1].
Related Catalog
References

[1]. Iqbal S, et al. In vitro Spectroscopic studies on drug interaction of cefpodoxime proxetil and H2 receptor blockers. Pak J Pharm Sci. 2019 Mar;32(2 (Supplementary)):881-887.

Density 1.6±0.1 g/cm3
Melting Point 111-113°C
Molecular Formula C21H27N5O9S2
Molecular Weight 557.597
Exact Mass 557.125000
PSA 234.51000
LogP 2.17
Index of Refraction 1.671
Storage condition -20?C Freezer
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2941905990

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87239-81-4 structure

87239-81-4

Literature: WO2004/48387 A1, ; Page 7-8 ;

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87239-81-4 structure

87239-81-4

Literature: Rodriguez, Juan C.; Hernandez, Ricardo; Gonzalez, Maritza; Rodriguez, Zalua; Tolon, Blanca; Velez, Herman; Valdes, Barbara; Lopez, Miguel A.; Fini, Adamo Farmaco, 2003 , vol. 58, # 5 p. 363 - 369

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87239-81-4 structure

87239-81-4

Literature: Farmaco, , vol. 58, # 5 p. 363 - 369

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87239-81-4 structure

87239-81-4

Literature: Farmaco, , vol. 58, # 5 p. 363 - 369

~%

87239-81-4 structure

87239-81-4

Literature: Farmaco, , vol. 58, # 5 p. 363 - 369

~%

87239-81-4 structure

87239-81-4

Literature: Farmaco, , vol. 58, # 5 p. 363 - 369

~%

87239-81-4 structure

87239-81-4

Literature: Farmaco, , vol. 58, # 5 p. 363 - 369

~%

87239-81-4 structure

87239-81-4

Literature: Farmaco, , vol. 58, # 5 p. 363 - 369

~%

87239-81-4 structure

87239-81-4

Literature: Farmaco, , vol. 58, # 5 p. 363 - 369
HS Code 2941905990