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2255-50-7

2255-50-7 structure
2255-50-7 structure
  • Name: Robustine
  • Chemical Name: robustine
  • CAS Number: 2255-50-7
  • Molecular Formula: C12H9NO3
  • Molecular Weight: 215.205
  • Catalog: Natural product Alkaloid
  • Create Date: 2017-01-10 11:55:49
  • Modify Date: 2025-08-24 20:06:19
  • Robustine, a furoquinoline alkaloid, from Dictamnus albus, exhibits inhibitory potency against human phosphodiesterase 5 (hPDE5A) in vitro[1].
Name robustine
Synonyms 4-Methoxyfuro[2,3-b]quinolin-8-ol
8-hydroxydictamnine
8-Hydroxy-4-methoxy-furo<2,3-b>chinolin
Furo[2,3-b]quinolin-8-ol, 4-methoxy-
8-Hydroxydictamnin
Robustine
Description Robustine, a furoquinoline alkaloid, from Dictamnus albus, exhibits inhibitory potency against human phosphodiesterase 5 (hPDE5A) in vitro[1].
Related Catalog
Target

PDE5A

References

[1]. Nam KW, et al. Inhibitory effects of furoquinoline alkaloids from Melicope confusa and Dictamnus albus against human phosphodiesterase 5 (hPDE5A) in vitro. Arch Pharm Res. 2005 Jun;28(6):675-9.
Density 1.4±0.1 g/cm3
Boiling Point 411.9±40.0 °C at 760 mmHg
Melting Point 148-149℃ (ethanol )
Molecular Formula C12H9NO3
Molecular Weight 215.205
Flash Point 202.9±27.3 °C
Exact Mass 215.058243
PSA 55.49000
LogP 2.73
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.708
Hazard Codes Xi
865878-14-4 structure

865878-14-4

~96%

2255-50-7 structure

2255-50-7

Literature: Boyd, Derek R.; Sharma, Narain D.; Carroll, Jonathan G.; Loke, Pui L.; O'Dowd, Colin R.; Allen, Christopher C. R. RSC Advances, 2013 , vol. 3, # 27 p. 10944 - 10955
865878-22-4 structure

865878-22-4

~%

2255-50-7 structure

2255-50-7

Literature: Boyd, Derek R.; Sharma, Narain D.; O'Dowd, Colin R.; Carroll, Jonathan G.; Loke, Pui L.; Allen, Christopher C. R. Chemical Communications, 2005 , # 31 p. 3989 - 3991
484-29-7 structure

484-29-7

~%

2255-50-7 structure

2255-50-7

Literature: Boyd, Derek R.; Sharma, Narain D.; Carroll, Jonathan G.; Loke, Pui L.; O'Dowd, Colin R.; Allen, Christopher C. R. RSC Advances, 2013 , vol. 3, # 27 p. 10944 - 10955
52336-79-5 structure

52336-79-5

~%

2255-50-7 structure

2255-50-7

Literature: Ramachandran,V.N. et al. Indian Journal of Chemistry, 1973 , vol. 11, p. 1088 - 1091
52336-81-9 structure

52336-81-9

~%

2255-50-7 structure

2255-50-7

Literature: Ramachandran,V.N. et al. Indian Journal of Chemistry, 1973 , vol. 11, p. 1088 - 1091
52336-80-8 structure

52336-80-8

~%

2255-50-7 structure

2255-50-7

Literature: Ramachandran,V.N. et al. Indian Journal of Chemistry, 1973 , vol. 11, p. 1088 - 1091
55727-61-2 structure

55727-61-2

~%

2255-50-7 structure

2255-50-7

Literature: Abdullaeva,Kh.A. et al. Chemistry of Natural Compounds, 1978 , vol. 14, p. 179 - 182 Khimiya Prirodnykh Soedinenii, 1978 , vol. 14, p. 219 - 223
111163-82-7 structure

111163-82-7

~%

2255-50-7 structure

2255-50-7

Literature: Boyd, Derek R.; Sharma, Narain D.; Carroll, Jonathan G.; Loke, Pui L.; O'Dowd, Colin R.; Allen, Christopher C. R. RSC Advances, 2013 , vol. 3, # 27 p. 10944 - 10955
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