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148-03-8

148-03-8 structure
148-03-8 structure
  • Name: Beta-Tocopherol
  • Chemical Name: β-tocopherol
  • CAS Number: 148-03-8
  • Molecular Formula: C28H48O2
  • Molecular Weight: 416.680
  • Catalog: Natural product Phenols
  • Create Date: 2018-12-24 13:00:14
  • Modify Date: 2024-01-06 12:14:41
  • (rel)-β-Tocopherol is a relative configuration of β-Tocopherol.(±)-β-Tocopherol is a lipid-soluble form of vitamin E with antioxidant activity. β-Tocopherol can inhibit tyrosinase activity and melanin synthesis. β-Tocopherol also can prevent the inhibition of cell growth and of PKC activity caused by d-alpha-tocopherol[1].

Name β-tocopherol
Synonyms beta-tocopherol
Cumotocopherol
p-Xylotocopherol
(2R)-2,5,8-Trimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]chroman-6-ol
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,8-trimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-, (2R)-
Neotocopherol
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,8-trimethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-, (2R)-rel-
β-tocopherol
(2R)-2,5,8-Trimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-6-chromanol
Tocopherol,rac-b
(2R)-2,5,8-trimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-ol
5,8-DIMETHYLTOCOL
EINECS 205-708-5
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,8-trimethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-, (2R)-
b-Tocopherol
Description (rel)-β-Tocopherol is a relative configuration of β-Tocopherol.(±)-β-Tocopherol is a lipid-soluble form of vitamin E with antioxidant activity. β-Tocopherol can inhibit tyrosinase activity and melanin synthesis. β-Tocopherol also can prevent the inhibition of cell growth and of PKC activity caused by d-alpha-tocopherol[1].
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. F. Bergel, et al. Studies on vitamin E. Part III. Observations on the structure of α- and β-tocopherol.

Density 0.9±0.1 g/cm3
Boiling Point 516.3±49.0 °C at 760 mmHg
Melting Point <25℃
Molecular Formula C28H48O2
Molecular Weight 416.680
Flash Point 204.7±24.1 °C
Exact Mass 416.365417
PSA 29.46000
LogP 11.44
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.495
Storage condition 2-8°C
Symbol GHS02 GHS07 GHS08 GHS09
GHS02, GHS07, GHS08, GHS09
Signal Word Danger
Hazard Statements H225-H304-H315-H336-H361f-H373-H411
Precautionary Statements P201-P210-P273-P301 + P310-P308 + P313-P331
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes F,Xn,N
Risk Phrases 11-38-48/20-51/53-62
Safety Phrases 36/37-61-62
RIDADR UN1208 3/PG 2

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Literature: DSM IP Assets B.V. Patent: EP2522647 A1, 2012 ; Location in patent: Page/Page column 15 ;

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148-03-8

Literature: Emerson; Smith Journal of the American Chemical Society, 1940 , vol. 62, p. 1869,1871 Full Text Show Details Jacob et al. Journal of the Chemical Society, 1939 , p. 542,544 Full Text Show Details Hoffmann-La Roche Patent: CH214350 , 1939 ;

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Literature: Karrer; Fritzsche Helvetica Chimica Acta, 1938 , vol. 21, p. 1234,1239 Full Text Show Details Karrer et al. Helvetica Chimica Acta, 1939 , vol. 22, p. 1139,1145

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148-03-8 structure

148-03-8

Literature: Green et al. Journal of the Chemical Society, 1959 , p. 3362,3369

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148-03-8

Literature: Hoffmann-La Roche Patent: US2411967 , 1938 ; Full Text Show Details Hoffmann-La Roche Patent: DE731972 , 1938 ; DRP/DRBP Org.Chem.