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Related CAS#:
2141-09-5 4277-43-4
6681-18-1

2141-09-5

2141-09-5 structure
2141-09-5 structure
  • Name: Magnoflorine
  • Chemical Name: (+)-magnoflorine iodide
  • CAS Number: 2141-09-5
  • Molecular Formula: C20H24NO4+
  • Molecular Weight: 342.408
  • Catalog: Natural product Alkaloid
  • Create Date: 2018-09-18 20:10:48
  • Modify Date: 2024-01-01 19:03:55
  • (+)-Magnoflorine (Magnoflorine) is an aporphine alkaloid found in Acoruscalamus, with anti-fungal activity, reduces the formation of C. albicans’ biofilm[1]. Anti-antidiabeticand anti-oxidative activity[2].
Name (+)-magnoflorine iodide
Synonyms 4H-Dibenzo[de,g]quinolinium, 5,6,6a,7-tetrahydro-1,11-dihydroxy-2,10-dimethoxy-6,6-dimethyl-, (6aS)-
Magflorine
escholin
Magnoflorine
Aporphine alkaloid
escholine
(6aS)-1,11-Dihydroxy-2,10-dimethoxy-6,6-dimethyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolinium
Thalictrine
UNII-NI8K6962K4
THALICTRIN
(S)-5,6,6a,7-Tetrahydro-1,11-dihydroxy-2,10-dimethoxy-6,6-dimethyl-4H-dibenzo[de,g]quinolinium
Esholine
Description (+)-Magnoflorine (Magnoflorine) is an aporphine alkaloid found in Acoruscalamus, with anti-fungal activity, reduces the formation of C. albicans’ biofilm[1]. Anti-antidiabeticand anti-oxidative activity[2].
Related Catalog
Target

Fungal[1]
References

[1]. Kim J, et al. Antifungal activity of magnoflorine against Candida strains. World J Microbiol Biotechnol. 2018 Oct 31;34(11):167.

[2]. Haque MA, et al. Magnoflorine Enhances LPS-Activated Pro-Inflammatory Responses via MyD88-Dependent Pathways in U937 Macrophages. Planta Med. 2018 Nov;84(17):1255-1264.
Melting Point 252ºC
Molecular Formula C20H24NO4+
Molecular Weight 342.408
Exact Mass 342.169983
PSA 58.92000
LogP -1.71
Storage condition 2-8C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
HQ1777600
CHEMICAL NAME :
4H-Dibenzo(de,g)quinolinium, 5,6,6a,7-tetrahydro-1,11-dihydroxy-2,10-dimethoxy-6,6 -dimethyl-, (S)-
CAS REGISTRY NUMBER :
2141-09-5
LAST UPDATED :
199503
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C20-H24-N-O4
MOLECULAR WEIGHT :
342.45

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
19600 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1979- Volume(issue)/page/year: 4,247,1981
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
138 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1979- Volume(issue)/page/year: 4,247,1981
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
20 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1979- Volume(issue)/page/year: 4,247,1981
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302 + H312 + H332
Precautionary Statements P261-P280-P301 + P312 + P330-P302 + P352 + P312-P304 + P340 + P312
RIDADR NONH for all modes of transport
RTECS HQ1777600

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title: CAS No. 2141-09-5 | Chemsrc address: https://m.chemsrc.com/en/baike/81016.html

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